Chemokine C-C-Motif Receptor 2 (CCR2) ELISA Kit for Human

Name: Human CCR2 ELISA Kit; Chemokine C-C-Motif Receptor 2; MyBioSource
Brand: MyBioSource
SKU: MBS096852
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS096852

MBS096852 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chemokine C-C-Motif Receptor 2 (CCR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Chemokine C-C-Motif Receptor 2 (CCR2), ELISA Kit

Full Product Name

Human Chemokine C-C-Motif Receptor 2 ELISA Kit

Product Gene Name

CCR2 elisa kit

Species Reactivity

Human

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

42,874 Da

OMIM

600242

3D Structure

ModBase 3D Structure for P32248

Other Notes

Small volumes of CCR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR2. It may not necessarily be applicable to this product.

NCBI GI #

4502641

NCBI GeneID

1236

NCBI Accession #

NP_001829.1

UniProt Primary Accession #

P32248

UniProt Related Accession #

P32248

GenBank Nucleotide #

NM_001838.3

NCBI Official Full Name

C-C chemokine receptor type 7

NCBI Official Synonym Full Names

chemokine (C-C motif) receptor 7

NCBI Official Symbol

CCR7

NCBI Official Synonym Symbols

BLR2; EBI1; CD197; CDw197; CMKBR7

UniProt Protein Name

C-C chemokine receptor type 7

UniProt Synonym Protein Names

BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor

Protein Family

C-C chemokine receptor

UniProt Gene Name

CCR7

UniProt Synonym Gene Names

CMKBR7; EBI1; EVI1; C-C CKR-7; CC-CKR-7; CCR-7; EBI1

UniProt Entry Name

CCR7_HUMAN

NCBI Protein Information

C-C chemokine receptor type 7; CCR-7; CC-CKR-7; C-C CKR-7; MIP-3 beta receptor; CC chemokine receptor 7; chemokine (C-C) receptor 7; Epstein-Barr virus induced gene 1; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced G-protein coupled receptor; lymphocyte-specific G protein-coupled peptide receptor; epstein-Barr virus-induced G-protein coupled receptor 1

NCBI Summary for CCR2

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008]

UniProt Comments for CCR2

CCR7: Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Motility/polarity/chemotaxis; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q12-q21.2

Cellular Component: cell surface; plasma membrane; integral to membrane; intracellular; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; C-C chemokine receptor activity

Biological Process: positive regulation of cell adhesion; positive regulation of interleukin-12 production; positive regulation of dendritic cell antigen processing and presentation; positive regulation of JNK cascade; response to lipopolysaccharide; elevation of cytosolic calcium ion concentration; positive regulation of T cell receptor signaling pathway; positive regulation of humoral immune response; dendritic cell chemotaxis; establishment of T cell polarity; inflammatory response; positive regulation of cell-matrix adhesion; positive regulation of filopodium formation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of hypersensitivity; positive regulation of phosphoinositide 3-kinase activity; negative thymic T cell selection; G-protein coupled receptor protein signaling pathway; positive regulation of protein kinase B signaling cascade; positive regulation of pseudopodium formation; myeloid dendritic cell chemotaxis; positive regulation of actin filament polymerization; regulation of interferon-gamma production; release of sequestered calcium ion into cytosol; positive regulation of protein kinase activity; ruffle organization and biogenesis; regulation of interleukin-1 beta secretion; immune response

Research Articles on CCR2

1. results indicate a regulatory influence of MR signaling on human T-cell migration and suggest a role for endogenous aldosterone in the redistribution of T-cell subsets to lymph nodes, involving CD62L, CCR7, and CXCR4.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CCR2 elisa kit

Reference Product	PubMed Publications
CD4 elisa kit	>813 publications with CCR2 and CD4
CCL21 elisa kit	>457 publications with CCR2 and CCL21
CCL19 elisa kit	>424 publications with CCR2 and CCL19
CCL5 elisa kit	>76 publications with CCR2 and CCL5
CXCL10 elisa kit	>72 publications with CCR2 and CXCL10
CCL20 elisa kit	>58 publications with CCR2 and CCL20
CXCL13 elisa kit	>50 publications with CCR2 and CXCL13
CXCL9 elisa kit	>29 publications with CCR2 and CXCL9
CCL25 elisa kit	>17 publications with CCR2 and CCL25

Pathways associated with CCR2 elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with CCR2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>526 publications with CCR2 and Neoplasms
Inflammation Antibodies	>356 publications with CCR2 and Inflammation
Necrosis Antibodies	>225 publications with CCR2 and Necrosis
Disease Models, Animal Antibodies	>135 publications with CCR2 and Disease Models, Animal
Lung Diseases Antibodies	>126 publications with CCR2 and Lung Diseases
Hypersensitivity Antibodies	>95 publications with CCR2 and Hypersensitivity
Neoplasms, Experimental Antibodies	>75 publications with CCR2 and Neoplasms, Experimental
Liver Diseases Antibodies	>67 publications with CCR2 and Liver Diseases
Carcinoma, Squamous Cell Antibodies	>47 publications with CCR2 and Carcinoma, Squamous Cell
Breast Neoplasms Antibodies	>45 publications with CCR2 and Breast Neoplasms

Organs/Tissues associated with CCR2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1880 publications with CCR2 and Blood
Lymph Node Antibodies	>750 publications with CCR2 and Lymph Node
Bone Marrow Antibodies	>229 publications with CCR2 and Bone Marrow
Lung Antibodies	>185 publications with CCR2 and Lung
Spleen Antibodies	>162 publications with CCR2 and Spleen
Thymus Antibodies	>102 publications with CCR2 and Thymus
Intestine Antibodies	>67 publications with CCR2 and Intestine
Brain Antibodies	>62 publications with CCR2 and Brain
Embryonic Tissue Antibodies	>31 publications with CCR2 and Embryonic Tissue
Eye Antibodies	>24 publications with CCR2 and Eye