Mouse CCL20 Active Protein – Cat# MBS969251

C-C Motif Chemokine 20 Protein (CCL20) Mouse Active Protein

Name: CCL20 Active Protein; C-C Motif Chemokine 20 Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS969251
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS969251

Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. {ECO:0000250}. More details

$245 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

C-C motif chemokine 20 protein (Ccl20), Active Protein

Full Product Name

Recombinant Mouse C-C motif chemokine 20 protein (Ccl20) (Active)

Product Gene Name

Ccl20 active protein

Product Synonym Gene Name

Larc; Scya20

Product Synonym Names

Beta-chemokine exodus-1; CC chemokine ST38; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha

Sequence

ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM

Host

E Coli

Form/Format

Lyophilized

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.

Molecular Weight

8.0 kDa

Sequence Positions

28-97aa

3D Structure

ModBase 3D Structure for O89093

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Species

Mus musculus (Mouse)

Biological Activity

Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml.

Endotoxin

Less than 1.0 EU/ug as determined by LAL method.

Protein Note

Protein will be provided with aseptic processing and endotoxin removal.

Product Categories/Family for Ccl20 active protein

Biological Active Protein; Immunology; Chemokine

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ccl20 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ccl20 purchase

MBS969251 is an active protein targeting Ccl20. Also known as Recombinant Mouse C-C motif chemokine 20 protein (Ccl20) (Active). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccl20. It may not necessarily be applicable to this product.

NCBI GI #

229092240

NCBI GeneID

20297

NCBI Accession #

NP_001153210.1

UniProt Primary Accession #

O89093

UniProt Secondary Accession #

Q9Z1X3

UniProt Related Accession #

O89093

GenBank Nucleotide #

NM_001159738.1

NCBI Official Full Name

C-C motif chemokine 20 isoform 2

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 20

NCBI Official Symbol

Ccl20

NCBI Official Synonym Symbols

CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1

UniProt Protein Name

C-C motif chemokine 20

UniProt Synonym Protein Names

Beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha; Small-inducible cytokine A20

Protein Family

C-C motif chemokine

UniProt Gene Name

Ccl20

UniProt Synonym Gene Names

Larc; Scya20; MIP-3-alpha

NCBI Protein Information

C-C motif chemokine 20

UniProt Comments for Ccl20

CCL20: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli 25922 and S.aureus 29213. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1 C5|1 42.69 cM

Cellular Component: extracellular space

Molecular Function: CCR6 chemokine receptor binding; chemokine activity; cytokine activity; protein binding

Biological Process: chemotaxis; G-protein coupled receptor protein signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity; positive regulation of interleukin-1 alpha biosynthetic process; positive regulation of nitric-oxide synthase biosynthetic process; regulation of T cell cytokine production

Research Articles on Ccl20

1. Taken together, these data show that, in adipose tissues, IL-17A contributes to exacerbating insulin resistance-enhancing IL-6 production and promotes the infiltration of Th17 cells in cooperation with TNFalpha; these findings represent a novel hypothesis for the association between IL-17A-producing cells and type 2 diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ccl20 active protein

Reference Product	PubMed Publications
Ccr6 active protein	>415 publications with Ccl20 and Ccr6
Cxcl10 active protein	>115 publications with Ccl20 and Cxcl10
Ccl5 active protein	>109 publications with Ccl20 and Ccl5
Cxcl2 active protein	>84 publications with Ccl20 and Cxcl2
Cxcl9 active protein	>63 publications with Ccl20 and Cxcl9
Cxcl5 active protein	>46 publications with Ccl20 and Cxcl5
Ccr5 active protein	>44 publications with Ccl20 and Ccr5
Ccl28 active protein	>14 publications with Ccl20 and Ccl28
Ccl9 active protein	>5 publications with Ccl20 and Ccl9

Pathways associated with Ccl20 active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
EBV LMP1 Signaling Pathway antibodies	EBV LMP1 Signaling Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram

Diseases associated with Ccl20 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>446 publications with Ccl20 and Inflammation
Necrosis Antibodies	>233 publications with Ccl20 and Necrosis
Skin Diseases Antibodies	>113 publications with Ccl20 and Skin Diseases
Carcinoma Antibodies	>101 publications with Ccl20 and Carcinoma
Lung Diseases Antibodies	>92 publications with Ccl20 and Lung Diseases
Hypersensitivity Antibodies	>63 publications with Ccl20 and Hypersensitivity
Liver Diseases Antibodies	>52 publications with Ccl20 and Liver Diseases
Asthma Antibodies	>50 publications with Ccl20 and Asthma
Fibrosis Antibodies	>34 publications with Ccl20 and Fibrosis
Neoplasms, Experimental Antibodies	>30 publications with Ccl20 and Neoplasms, Experimental

Organs/Tissues associated with Ccl20 active protein

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>14 publications with Ccl20 and Thymus
Mammary Gland Antibodies	>6 publications with Ccl20 and Mammary Gland
Testis Antibodies	>1 publications with Ccl20 and Testis