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C-C Motif Chemokine 22 Protein (CCL22) Mouse Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS969253

Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B-lymphocytes with T-cells in immune responses. More details

$550 / 0.02 mg (Mammalian-Cell) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-C motif chemokine 22 protein (Ccl22), Active Protein
Full Product Name
Recombinant Mouse C-C motif chemokine 22 protein (Ccl22) (Active)
Product Gene Name
Ccl22 active protein
Product Synonym Gene Name
Abcd1; Scya22
Product Synonym Names
Activated B and dendritic cell-derived; Small-inducible cytokine A22
Sequence
GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS
Host
E Coli
Form/Format
Lyophilized
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
Molecular Weight
7.8 kDa
Sequence Positions
25-92aa
3D Structure
ModBase 3D Structure for O88430
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Species
Mus musculus (Mouse)
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human activated lymphocytes is in a concentration range of 10-100 ng/ml.
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Protein Note
Protein will be provided with aseptic processing and endotoxin removal.

Product Categories/Family for Ccl22 active protein

Biological Active Protein; Immunology; Chemokine
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of Ccl22 active protein

Mouse CCL22 Active Protein – Cat# MBS969253

Other Notes

Small volumes of Ccl22 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ccl22 purchase

MBS969253 is an active protein targeting Ccl22. Also known as Recombinant Mouse C-C motif chemokine 22 protein (Ccl22) (Active). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccl22. It may not necessarily be applicable to this product.

NCBI GI #
6677879
NCBI GeneID
20299
NCBI Accession #
NP_033163.1
UniProt Primary Accession #
O88430
UniProt Related Accession #
O88430
GenBank Nucleotide #
NM_009137.2
NCBI Official Full Name
C-C motif chemokine 22
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 22
NCBI Official Symbol
Ccl22
NCBI Official Synonym Symbols
MDC; DCBCK; ABCD-1; Scya22
UniProt Protein Name
C-C motif chemokine 22
UniProt Synonym Protein Names
Activated B and dendritic cell-derived; CC chemokine ABCD-1; Small-inducible cytokine A22
Protein Family
C-C motif chemokine
UniProt Gene Name
Ccl22
UniProt Synonym Gene Names
Abcd1; Scya22
NCBI Protein Information
C-C motif chemokine 22

UniProt Comments for Ccl22

CCL22: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8|8 C5

Cellular Component: extracellular space

Molecular Function: CCR chemokine receptor binding; chemokine activity

Biological Process: G-protein coupled receptor protein signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity
Show more

Research Articles on Ccl22

1. Intratumoral administration of anti-CCL22 antibody inhibited B16F10 melanoma growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ccl22 active protein

 Reference Product  PubMed Publications
 Ccl17 active protein  >378 publications with Ccl22 and Ccl17
 Ccr4 active protein  >238 publications with Ccl22 and Ccr4
 Ccl5 active protein  >96 publications with Ccl22 and Ccl5
 Ccl3 active protein  >67 publications with Ccl22 and Ccl3
 Ccl11 active protein  >62 publications with Ccl22 and Ccl11
 Ccl4 active protein  >57 publications with Ccl22 and Ccl4
 Ccr7 active protein  >45 publications with Ccl22 and Ccr7
 Ccl7 active protein  >26 publications with Ccl22 and Ccl7
 Ccr1 active protein  >17 publications with Ccl22 and Ccr1

Pathways associated with Ccl22 active protein

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with Ccl22 active protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >215 publications with Ccl22 and Inflammation
 Hypersensitivity Antibodies  >155 publications with Ccl22 and Hypersensitivity
 Respiratory Tract Diseases Antibodies  >127 publications with Ccl22 and Respiratory Tract Diseases
 Necrosis Antibodies  >89 publications with Ccl22 and Necrosis
 Dermatitis, Atopic Antibodies  >80 publications with Ccl22 and Dermatitis, Atopic
 Respiratory Hypersensitivity Antibodies  >67 publications with Ccl22 and Respiratory Hypersensitivity
 Liver Diseases Antibodies  >19 publications with Ccl22 and Liver Diseases
 Lung Neoplasms Antibodies  >16 publications with Ccl22 and Lung Neoplasms
 Pneumonia Antibodies  >16 publications with Ccl22 and Pneumonia
 Cardiovascular Diseases Antibodies  >15 publications with Ccl22 and Cardiovascular Diseases

Organs/Tissues associated with Ccl22 active protein

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >142 publications with Ccl22 and Thymus
 Skin Antibodies  >138 publications with Ccl22 and Skin
 Lymph Node Antibodies  >68 publications with Ccl22 and Lymph Node
 Spleen Antibodies  >36 publications with Ccl22 and Spleen
 Thyroid Antibodies  >3 publications with Ccl22 and Thyroid
 Salivary Gland Antibodies  >3 publications with Ccl22 and Salivary Gland
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