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Beta-Defensin 104 Protein (DEFB104A) Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS969424

Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. {ECO:0000269|PubMed:11481241}. More details

$245 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Beta-defensin 104 protein (DEFB104A), Active Protein
Full Product Name
Recombinant Human Beta-defensin 104 protein (DEFB104A) (Active)
Product Gene Name
Product Synonym Gene Name
DEFB104; DEFB4;; DEFB104B
Product Synonym Names
Beta-defensin 4; DEFB-4; hBD-4; Defensin; beta 104
Sequence
EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
Host
E Coli
Form/Format
Lyophilized
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
Molecular Weight
6.0 kDa
Sequence Positions
23-72aa
3D Structure
ModBase 3D Structure for Q8WTQ1
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Species
Homo sapiens (Human)
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 0.1-100.0 ng/ml.
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Protein Note
Protein will be provided with aseptic processing and endotoxin removal.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DEFB104A active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DEFB104A purchase

MBS969424 is an active protein targeting DEFB104A. Also known as Recombinant Human Beta-defensin 104 protein (DEFB104A) (Active). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFB104A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-defensin 104
NCBI Official Synonym Full Names
defensin beta 104B
NCBI Official Symbol
DEFB104B
NCBI Official Synonym Symbols
BD-4; hBD-4; DEFB-4
UniProt Protein Name
Beta-defensin 104
UniProt Synonym Protein Names
Beta-defensin 4; BD-4; DEFB-4; hBD-4; Defensin, beta 104
Protein Family
UniProt Gene Name
DEFB104A
UniProt Synonym Gene Names
DEFB104; DEFB4; BD-4; DEFB-4; hBD-4
NCBI Protein Information
beta-defensin 104

NCBI Summary for DEFB104A

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104B, represents the more telomeric copy. [provided by RefSeq, Oct 2014]
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UniProt Comments for DEFB104A

defensin, beta 4: Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. Belongs to the beta-defensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: cell surface

Molecular Function: chemoattractant activity

Biological Process: defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; innate immune response; monocyte chemotaxis; positive chemotaxis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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