Glutathione Peroxidase 1 (GPX1) Human Recombinant Protein

MBS969530 is a recombinant protein targeting GPX1. Also known as Recombinant Human Glutathione peroxidase 1. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Protects the hoglobin in erythrocytes from oxidative breakdown.

cDNA sequence coding for human glutathione peroxidase.Sukenaga Y., Ishida K., Takeda T., Takagi K.Nucleic Acids Res. 15:7178-7178(1987) Nucleotide sequence of a human gene for glutathione peroxidase.Ishida K., Morino T., Takagi K., Sukenaga Y.Nucleic Acids Res. 15:10051-10051(1987) Sequence of a cDNA coding for human glutathione peroxidase confirms TGA encodes active site selenocysteine.Mullenbach G.T., Tabrizi A., Irvine B.D., Bell G.I., Hallewell R.A.Nucleic Acids Res. 15:5484-5484(1987) Isolation and chromosomal localization of the human glutathione peroxidase gene.Chada S., le Beau M.M., Casey L., Newburger P.E.Genomics 6:268-271(1990) Structure and function of the 5'-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1) .Moscow J.A., Morrow C.S., He R., Mullenbach G.T., Cowan K.H.J. Biol. Chem. 267:5949-5958(1992) NIEHS SNPs programThe DNA sequence, annotation and analysis of human chromosome 3.Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.Nature 440:1194-1198(2006) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014) Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1.Structural genomics consortium (SGC) Submitted (FEB-2009) to the PDB data bankLow yield of polymorphisms from EST blast searching analysis of genes related to oxidative stress and verification of the P197L polymorphism in GPX1.Forsberg L., de Faire U., Morgenstern R.3.0.CO;2-5>Hum. Mutat. 13:294-300(1999) Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer.Kote-Jarai Z., Durocher F., Edwards S.M., Hamoudi R., Jackson R.A., Ardern-Jones A., Murkin A., Dearnaley D.P., Kirby R., Houlston R., Easton D.F., Eeles R.Prostate Cancer Prostatic Dis. 5:189-192(2002) Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients.Hamanishi T., Furuta H., Kato H., Doi A., Tamai M., Shimomura H., Sakagashira S., Nishi M., Sasaki H., Sanke T., Nanjo K.Diabetes 53:2455-2460(2004) Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant.Ichimura Y., Habuchi T., Tsuchiya N., Wang L., Oyama C., Sato K., Nishiyama H., Ogawa O., Kato T.J. Urol. 172:728-732(2004)

Small volumes of GPX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.