Canine GABPalpha ELISA Kit – Cat# MBS097694

Ga Binding Protein Transcription Factor Alpha (GABPalpha) ELISA Kit for Canine

Name: Canine GABPalpha ELISA Kit; Ga Binding Protein Transcription Factor Alpha; MyBioSource
Brand: MyBioSource
SKU: MBS097694
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS097694

MBS097694 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GA Binding Protein Transcription Factor Alpha (GABPalpha) ELISA Kit target analytes in biological samples. The concentration… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

GA Binding Protein Transcription Factor Alpha (GABPalpha), ELISA Kit

Full Product Name

Canine GA Binding Protein Transcription Factor Alpha ELISA Kit

Product Gene Name

GABPalpha elisa kit

Species Reactivity

Canine

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

51,295 Da

OMIM

600609

3D Structure

ModBase 3D Structure for Q06546

Other Notes

Small volumes of GABPalpha elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GABPalpha. It may not necessarily be applicable to this product.

NCBI GI #

383615289

NCBI GeneID

2551

NCBI Accession #

AFH41795.1

UniProt Primary Accession #

Q06546

UniProt Secondary Accession #

Q12939

UniProt Related Accession #

Q06546

NCBI Official Full Name

GA binding protein transcription factor alpha subunit 60kDa

NCBI Official Synonym Full Names

GA binding protein transcription factor, alpha subunit 60kDa

NCBI Official Symbol

GABPA

NCBI Official Synonym Symbols

NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07

UniProt Protein Name

GA-binding protein alpha chain

UniProt Synonym Protein Names

Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60

UniProt Gene Name

GABPA

UniProt Synonym Gene Names

E4TF1A; GABP subunit alpha

UniProt Entry Name

GABPA_HUMAN

NCBI Protein Information

GA-binding protein alpha chain; GABP subunit alpha; transcription factor E4TF1-60; nuclear respiratory factor 2 alpha subunit; nuclear respiratory factor 2 subunit alpha; human nuclear respiratory factor-2 subunit alpha; GA binding protein transcription factor alpha subunit 60kDa

NCBI Summary for GABPalpha

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]

UniProt Comments for GABPalpha

GABPA: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. Belongs to the ETS family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: nucleoplasm; nuclear chromatin; nucleus

Molecular Function: protein binding; DNA binding; protein heterodimerization activity; transcription coactivator activity; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; in utero embryonic development; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cell differentiation; negative regulation of megakaryocyte differentiation

Research Articles on GABPalpha

1. results demonstrate the functional importance of the C/EBPalpha C-terminus beyond the bZIP DNA-binding and dimerization region, which may mediate cooperative activation by C/EBPalpha and GABP of myeloid-specific genes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GABPalpha elisa kit

Reference Product	PubMed Publications
GABPB1 elisa kit	>20 publications with GABPalpha and GABPB1
TFAM elisa kit	>11 publications with GABPalpha and TFAM
SP1 elisa kit	>8 publications with GABPalpha and SP1
KEAP1 elisa kit	>2 publications with GABPalpha and KEAP1

Pathways associated with GABPalpha elisa kit

Products by Pathway	Pathway Diagram
Energy Metabolism Pathway antibodies	Energy Metabolism Pathway Diagram
Mitochondrial Biogenesis Pathway antibodies	Mitochondrial Biogenesis Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram
Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies	Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram

Diseases associated with GABPalpha elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>10 publications with GABPalpha and Nervous System Diseases
Disease Models, Animal Antibodies	>9 publications with GABPalpha and Disease Models, Animal
Inflammation Antibodies	>6 publications with GABPalpha and Inflammation
Cardiovascular Diseases Antibodies	>5 publications with GABPalpha and Cardiovascular Diseases
Necrosis Antibodies	>5 publications with GABPalpha and Necrosis
Neurobehavioral Manifestations Antibodies	>3 publications with GABPalpha and Neurobehavioral Manifestations
Fatty Liver Antibodies	>3 publications with GABPalpha and Fatty Liver
Liver Diseases Antibodies	>3 publications with GABPalpha and Liver Diseases
Abnormalities, Multiple Antibodies	>3 publications with GABPalpha and Abnormalities, Multiple
Heart Diseases Antibodies	>2 publications with GABPalpha and Heart Diseases

Organs/Tissues associated with GABPalpha elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>19 publications with GABPalpha and Blood
Liver Antibodies	>16 publications with GABPalpha and Liver
Muscle Antibodies	>13 publications with GABPalpha and Muscle
Brain Antibodies	>13 publications with GABPalpha and Brain
Heart Antibodies	>6 publications with GABPalpha and Heart
Testis Antibodies	>4 publications with GABPalpha and Testis
Lung Antibodies	>3 publications with GABPalpha and Lung
Embryonic Tissue Antibodies	>3 publications with GABPalpha and Embryonic Tissue
Connective Tissue Antibodies	>3 publications with GABPalpha and Connective Tissue
Thyroid Antibodies	>2 publications with GABPalpha and Thyroid