Donkey SIGLEC1 ELISA Kit – Cat# MBS098660

Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) ELISA Kit for Donkey

Name: Donkey SIGLEC1 ELISA Kit; Sialic Acid Binding Ig Like Lectin 1; MyBioSource
Brand: MyBioSource
SKU: MBS098660
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS098660

MBS098660 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) ELISA Kit target analytes in biological samples. The concentration… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1), ELISA Kit

Full Product Name

Donkey Sialic Acid Binding Ig Like Lectin 1 ELISA Kit

Product Gene Name

SIGLEC1 elisa kit

Species Reactivity

Donkey

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

182,624 Da

OMIM

600751

3D Structure

ModBase 3D Structure for Q9BZZ2

Other Notes

Small volumes of SIGLEC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SIGLEC1. It may not necessarily be applicable to this product.

NCBI GI #

13489095

NCBI GeneID

6614

NCBI Accession #

NP_075556.1

UniProt Primary Accession #

Q9BZZ2

UniProt Secondary Accession #

Q96DL4; Q9GZS5; Q9H1H6; Q9H1H7; Q9H7L7

UniProt Related Accession #

Q9BZZ2

GenBank Nucleotide #

NM_023068.3

NCBI Official Full Name

sialoadhesin

NCBI Official Synonym Full Names

sialic acid binding Ig-like lectin 1, sialoadhesin

NCBI Official Symbol

SIGLEC1

NCBI Official Synonym Symbols

SN; CD169; SIGLEC-1; dJ1009E24.1

UniProt Protein Name

Sialoadhesin

UniProt Synonym Protein Names

Sialic acid-binding Ig-like lectin 1

Protein Family

Sialoadhesin

UniProt Gene Name

SIGLEC1

UniProt Synonym Gene Names

SN; Siglec-1

UniProt Entry Name

SN_HUMAN

NCBI Protein Information

sialoadhesin; sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1

NCBI Summary for SIGLEC1

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for SIGLEC1

SIGLEC1: Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hemopoiesis. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: plasma membrane; extracellular region; integral to membrane

Molecular Function: carbohydrate binding

Biological Process: cell-cell adhesion; cell-matrix adhesion; endocytosis; inflammatory response

Research Articles on SIGLEC1

1. Siglec-1 may play a proinflammatory role in stimulating lymphocyte proliferation and activation in rheumatoid arthritis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SIGLEC1 elisa kit

Reference Product	PubMed Publications
RSAD2 elisa kit	>2 publications with SIGLEC1 and RSAD2
MUC1 elisa kit	>2 publications with SIGLEC1 and MUC1
SPN elisa kit	>1 publications with SIGLEC1 and SPN

Pathways associated with SIGLEC1 elisa kit

Products by Pathway	Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram

Organs/Tissues associated with SIGLEC1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>85 publications with SIGLEC1 and Blood
Bone Antibodies	>25 publications with SIGLEC1 and Bone
Spleen Antibodies	>22 publications with SIGLEC1 and Spleen
Liver Antibodies	>13 publications with SIGLEC1 and Liver
Ovary Antibodies	>3 publications with SIGLEC1 and Ovary
Lung Antibodies	>3 publications with SIGLEC1 and Lung
Brain Antibodies	>3 publications with SIGLEC1 and Brain
Kidney Antibodies	>3 publications with SIGLEC1 and Kidney
Eye Antibodies	>2 publications with SIGLEC1 and Eye
Uterus Antibodies	>2 publications with SIGLEC1 and Uterus