Fibroblast Growth Factor 22 (FGF22) Active Protein

Name: FGF22 Active Protein; MyBioSource
Brand: MyBioSource
SKU: MBS650521
Price: 750 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650521

Fibroblast growth factor 22, a protein which in humans is encoded by the FGF22 gene, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological… More details

$750 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fibroblast Growth Factor 22 (FGF22), Active Protein

Full Product Name

Fibroblast Growth Factor 22, Recombinant, Human (FGF22)

Product Gene Name

FGF22 active protein

Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be
Thr- Pro-Ser-Al a-Ser.

Host

E Coli

Form/Format

Supplied as a lyophilized powder without additives. Reconstitution: It is recommended to reconstitute the lyophilized Recombinant Human FGF-22 sterile 18M -cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Purity/Purification

Highly Purified
95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile dH2O or buffer of choice and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

17.17kD

Chromosome Location

Chromosome: 19; NC_000019.9 (639926..643604). Location: 19p13.3

OMIM

605831

3D Structure

ModBase 3D Structure for Q9HCT0

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Measured in a cell proliferation assay using IEC6 cell line (20ng/ml can stimulate the cell proliferation of IEC6 cell line).

Dimers and Aggregates

1% as determined by silver-stained SDS-PAGE gel analysis.

Endotoxin Level

0.1ng/ug (IEU/ug) of Recombinant Human FGF-22.

Product Categories/Family for FGF22 active protein

Growth Factors; Cytokines; Growth Factors-FGF

Other Notes

Small volumes of FGF22 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF22 purchase

MBS650521 is an active protein targeting FGF22. Also known as Fibroblast Growth Factor 22, Recombinant, Human (FGF22). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF22. It may not necessarily be applicable to this product.

NCBI GI #

10190672

NCBI GeneID

27006

NCBI Accession #

NP_065688.1

UniProt Primary Accession #

Q9HCT0

UniProt Secondary Accession #

B2RPH4

UniProt Related Accession #

O60371; Q9HCT0

GenBank Nucleotide #

NM_020637.1

NCBI Official Full Name

fibroblast growth factor 22

NCBI Official Synonym Full Names

fibroblast growth factor 22

NCBI Official Symbol

FGF22

UniProt Protein Name

Fibroblast growth factor 22

Protein Family

Fibroblast growth factor

UniProt Gene Name

FGF22

UniProt Entry Name

FGF22_HUMAN

NCBI Protein Information

fibroblast growth factor 22; FGF-22

NCBI Summary for FGF22

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. [provided by RefSeq]

UniProt Comments for FGF22

Function: May be involved in hair development.

Subunit structure: Interacts with FGFBP1. Ref.6

Subcellular location: Secreted

Potential.

Sequence similarities: Belongs to the heparin-binding growth factors family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FGF22 active protein

Products by Pathway	Pathway Diagram
Downstream Signaling Of Activated FGFR Pathway antibodies	Downstream Signaling Of Activated FGFR Pathway Diagram
FGFR Ligand Binding And Activation Pathway antibodies	FGFR Ligand Binding And Activation Pathway Diagram
FGFR1 Ligand Binding And Activation Pathway antibodies	FGFR1 Ligand Binding And Activation Pathway Diagram
FGFR1b Ligand Binding And Activation Pathway antibodies	FGFR1b Ligand Binding And Activation Pathway Diagram
FGFR2 Ligand Binding And Activation Pathway antibodies	FGFR2 Ligand Binding And Activation Pathway Diagram
FGFR2b Ligand Binding And Activation Pathway antibodies	FGFR2b Ligand Binding And Activation Pathway Diagram
FRS2-mediated Cascade Pathway antibodies	FRS2-mediated Cascade Pathway Diagram
IRS-mediated Signalling Pathway antibodies	IRS-mediated Signalling Pathway Diagram
IRS-related Events Pathway antibodies	IRS-related Events Pathway Diagram
Insulin Receptor Signalling Cascade Pathway antibodies	Insulin Receptor Signalling Cascade Pathway Diagram

Diseases associated with FGF22 active protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with FGF22 and Breast Neoplasms
Neoplasms Antibodies	>1 publications with FGF22 and Neoplasms

Organs/Tissues associated with FGF22 active protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with FGF22 and Brain