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FGG native protein :: Fibrinogen Native Protein

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Catalog # MBS537444
Unit / Price
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  1 g  /  $355 +1 FREE 8GB USB
FGG native protein
Product Name

Fibrinogen (FGG), Native Protein

Popular Item
Full Product Name

Fibrinogen protein

Product Synonym Names
Fg protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P12799
Host
Human
Purity/Purification
> 95% pure
Form/Format
20mM sodium citrate-HCl buffer, pH 7.4. Plasminogen Depleted.
Concentration
43.77 mg/ml (lot specific)
Source Note
Human plasma
Protein Type
Native
Biological Significance
Fibrinogen (factor I) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. This is achieved through processes in the coagulation cascade that activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin.
Biohazard Information
Human plasma tested negative against anti-HIV1/2, anti-HTLV I & II, anti-HCV, HbsAg, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors also screened for Creutzfeldt-Jakob Disease.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles
Other Notes
Small volumes of FGG native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FGG native protein
Highly purified native Fibrinogen protein
Product Categories/Family for FGG native protein
Applications Tested/Suitable for FGG native protein
User optimized
Application Notes for FGG native protein
100% Clottable
NCBI/Uniprot data below describe general gene information for FGG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
50,244 Da[Similar Products]
NCBI Official Full Name
fibrinogen
NCBI Official Symbol
NCBI Protein Information
fibrinogen gamma-B chain
UniProt Protein Name
Fibrinogen gamma-B chain
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Gamma'  [Similar Products]
UniProt Entry Name
FIBG_BOVIN
UniProt Comments for FGG
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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