ELISA KitInterleukins (IL) are a type of cytokine (protein) made in response to pathogens and other antigens that regulate and mediate inflammatory and immune responses. Interleukins are secreted proteins that bind to their specific receptors and play a role in intercellular communication among leukocytes. The relations between immune cells and inflammatory cells is facilitated by proteins, termed as interleukins (IL). Interleukins are able to promote cell growth, differentiation, and functional activation. Seven interleukins have been described; each has unique biological activities as well as some that overlap with the others. Interleukins often influence other interleukin synthesis and actions. For instance, IL-1 promotes lymphocyte activation that leads to the release of IL-2.
Macrophages, cells that play important roles in both immunity and inflammation, produce IL 1 and IL 6, whereas T cells produce IL 2-IL 6 and bone marrow stromal cells produce IL 7. IL 1 and IL 6 not only play important roles in immune cell function, but also stimulate a spectrum of inflammatory cell types and induce fever. The growth and differentiation of eosinophils is markedly enhanced by IL 5. IL 2 is a potent proliferative signal for T cells, natural killer cells, and lymphokine-activated killer cells. IL 1, IL 3, IL 4, and IL 7 enhance the development of a variety of hematopoietic precursors. IL 4-IL 6 also serve to enhance B cell proliferation and antibody production. The understanding of interleukin structure and function has led to new and important insights into the fundamental biology of immunity and inflammation.
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ELISA Kit