AAA35515.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
alpha-1 acid glycoprotein
NCBI Official Synonym Full Names
orosomucoid 1
NCBI Protein Information
alpha-1-acid glycoprotein 1
UniProt Protein Name
Alpha-1-acid glycoprotein 1
UniProt Synonym Protein Names
Orosomucoid-1; OMD 1
UniProt Synonym Gene Names
UniProt Entry Name
A1AG1_HUMAN
NCBI Summary for ORM1
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]
UniProt Comments for ORM1
ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q32
Cellular Component: extracellular region; extracellular space
Molecular Function: protein binding
Biological Process: acute-phase response; inflammatory response; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; platelet degranulation; regulation of immune system process
Research Articles on ORM1
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Pathways associated with ORM1 antigen
Diseases associated with ORM1 antigen
Organs/Tissues associated with ORM1 antigen
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