Canonical Wnt - Zebrafish Pathway

bone morphogenetic protein 4, ELISA Kit

Rat Bone morphogenetic protein 4, BMP-4 ELISA Kit

(#MBS701899)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

Rat Bone morphogenetic protein 4; BMP-4 ELISA Kit; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME; bone morphogenetic protein 2B; bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Rat

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates

Detection Range

7.8 pg/ml -500 pg/ml.

Sensitivity

The minimum detectable dose of rat BMP-4 is typically less than 1.95 pg/ml. The sensitivity of this assay, or Lower...

Popular

24-Strip-Wells (LIMIT 1)

Neurogenin 1, Polyclonal Antibody

Goat anti-Neurogenin 1 (zebrafish) Antibody

(#MBS422096)

Gene Names:

neurog1; ngn1; ngr1; cb260; zNgn1; neurod3; chunp6899

Other Names:

neurogenin 1; neurogenic differentiation 3; neurogenin1; neurog1 antibody; neurogenin 1 antibody; cb260 antibody; chunp6899 antibody; neurod3 antibody; ngn1 antibody; ngr1 antibody; zNgn1 antibody; ne...

Host/Reactivities:

Host: Goat / Reactivity: Expected from sequence similarity: Zebrafish

Purification:

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Applications:

Peptide ELISA (EIA)

Bone Morphogenetic Protein 4, ELISA Kit

Rat Bone Morphogenetic Protein 4 ELISA Kit

(#MBS721467)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Rat

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1 ng/ml

Pituitary homeobox 2 (pitx2), Recombinant Protein

Recombinant Danio rerio Pituitary homeobox 2 (pitx2)

(#MBS1440577)

Gene Names:

pitx2; pitx2a; pitx2c; zgc:110508

Other Names:

pituitary homeobox 2; paired-like homeodomain 2

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1445

$2780

$4040

$7220

Bone Morphogenetic Protein 4, ELISA Kit

Human Bone Morphogenetic Protein 4 ELISA Kit

(#MBS729617)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Human

Assay Type

Competitive or Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Sox9a, Polyclonal Antibody

Goat anti-Sox9a (zebrafish) Antibody

(#MBS421688)

Gene Names:

sox9a; jef; wu:fj17b12; zgc:111921

Other Names:

SRY-box containing gene 9a; fj17b12; wu: fj17b12; zgc: 111921; jellyfish; sox9a antibody; SRY-box containing gene 9a antibody; fj17b12 antibody; jef antibody; wu: fj17b12 antibody; zgc: 111921 antibod...

Host/Reactivities:

Host: Goat / Reactivity: Expected from sequence similarity: Zebrafish

Purification:

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Applications:

Peptide ELISA (EIA)

Neurogenin 1, Blocking Peptide

Neurogenin 1 Immunizing Peptide

(#MBS425604)

Gene Names:

neurog1; ngn1; ngr1; cb260; zNgn1; neurod3; chunp6899

Other Names:

neurogenin 1; neurogenic differentiation 3; neurogenin1; Neurogenin 1 (zebrafish); neurogenin-1

Host/Reactivities:

Reactivity: Zebrafish

Sox9b, Polyclonal Antibody

Goat anti-Sox9b (zebrafish aa5-18) Antibody

(#MBS423164)

Gene Names:

Sox9b; fb18d01; wu:fb18d01

Other Names:

SRY-box containing gene 9b; wu: fb18d01; fb18d01 antibody; SRY-box containing gene 9b antibody; wu: fb18d01 antibody; sox9b antibody; Sox9b (zebrafish aa5-18); SRY (sex determining region Y)-box 9b

Host/Reactivities:

Host: Goat / Reactivity: Expected from sequence similarity: Zebrafish

Purification:

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Applications:

Peptide ELISA (EIA)

Bone Morphogenetic Protein 4, ELISA Kit

Rabbit Bone Morphogenetic Protein 4 ELISA Kit

(#MBS731893)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Rabbit

Assay Type

Competitive or Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

50-1000pg/mL

Sensitivity

1.0pg/mL

Popular

Bone Morphogenetic Protein 4, ELISA Kit

Guinea pig Bone Morphogenetic Protein 4 ELISA Kit

(#MBS726296)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Guinea Pig

Assay Type

Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

50-1000pg/mL

Sensitivity

1.0pg/mL

Connexin 43, ELISA Kit

Bovine Connexin 43 ELISA Kit

(#MBS737036)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Bovine

Assay Type

Quantitative Competitive

Samples

Serum, Plasma, Cell Culture Supernatants, Body Fluid And Tissue Homogenate

Sensitivity

0.1 ng/mL.

Connexin 43, ELISA Kit

Porcine Connexin 43 ELISA Kit

(#MBS741769)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Porcine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

2.5-50ng/mL

Sensitivity

0.1ng/mL

Bone Morphogenetic Protein 4, ELISA Kit

Goat Bone Morphogenetic Protein 4 ELISA Kit

(#MBS735137)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Goat

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Connexin 43, ELISA Kit

Chicken Connexin 43 ELISA Kit

(#MBS742680)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Chicken

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Sox9b, Polyclonal Antibody

Goat anti-Sox9b (zebrafish) Antibody

(#MBS421972)

Gene Names:

sox9b; fb18d01; wu:fb18d01

Other Names:

SRY-box containing gene 9b; wu: fb18d01; sox9b antibody; SRY-box containing gene 9b antibody; fb18d01 antibody; wu: fb18d01 antibody; Sox9b (zebrafish); SRY (sex determining region Y)-box 9b

Host/Reactivities:

Host: Goat / Reactivity: Expected from sequence similarity: Zebrafish

Purification:

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Applications:

Peptide ELISA (EIA)

Bone Morphogenetic Protein 4, ELISA Kit

Canine Bone Morphogenetic Protein 4 ELISA Kit

(#MBS741547)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Canine

Assay Type

Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

50-1000pg/mL

Sensitivity

1.0pg/mL

Homeobox protein OTX2 (otx2), Recombinant Protein

Recombinant Danio rerio Homeobox protein OTX2 (otx2)

(#MBS1325244)

Gene Names:

otx2; otx2b; zOtx2; zotx-2; id:ibd2915; zgc:136535

Other Names:

homeobox protein OTX2; orthodenticle homeobox 2b

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1420

$2735

$3970

$7175

Connexin 43, ELISA Kit

Canine Connexin 43 ELISA Kit

(#MBS735563)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Canine

Assay Type

Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Sox9b, Polyclonal Antibody

Goat anti-Sox9b (zebrafish aa248-259) Antibody

(#MBS422988)

Gene Names:

Sox9b; fb18d01; wu:fb18d01

Other Names:

SRY-box containing gene 9b; wu: fb18d01; fb18d01 antibody; SRY-box containing gene 9b antibody; wu: fb18d01 antibody; sox9b antibody; Sox9b (zebrafish aa248-259); SRY (sex determining region Y)-box 9b

Host/Reactivities:

Host: Goat / Reactivity: Expected from sequence similarity: Zebrafish

Purification:

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Applications:

Peptide ELISA (EIA)

Sox9b, Blocking Peptide

Sox9b Immunizing Peptide

(#MBS426967)

Gene Names:

sox9b; fb18d01; wu:fb18d01

Other Names:

SRY-box containing gene 9b; wu: fb18d01; Sox9b (zebrafish); SRY (sex determining region Y)-box 9b

Host/Reactivities:

Reactivity: Zebrafish

Connexin 43, ELISA Kit

Rabbit Connexin 43 ELISA Kit

(#MBS730023)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Rabbit

Assay Type

Competitive or Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Connexin 43, ELISA Kit

Guinea pig Connexin 43 ELISA Kit

(#MBS721593)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Guinea Pig

Assay Type

Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Connexin 43, ELISA Kit

Rat Connexin 43 ELISA Kit

(#MBS730091)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Rat

Assay Type

Competitive or Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/ml

Bone Morphogenetic Protein 4, ELISA Kit

Bovine Bone Morphogenetic Protein 4 ELISA Kit

(#MBS736740)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Bovine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Bone Morphogenetic Protein 4, ELISA Kit

Sheep Bone Morphogenetic Protein 4 ELISA Kit

(#MBS735168)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Sheep

Assay Type

Quantitative Competitive

Samples

Serum, plasma, cell culture supernatants, body fluid and tissue homogenate

Sensitivity

1.0 pg/mL

Connexin 43, ELISA Kit

Mouse Connexin 43 ELISA Kit

(#MBS727188)

Gene Names:

cx43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Mouse

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Neurogenin-1 (neurog1), Recombinant Protein

Recombinant Danio rerio Neurogenin-1 (neurog1)

(#MBS1023530)

Gene Names:

neurog1; neurod3; ngn1; ngr1; cb260; zNgn1; chunp6899

Other Names:

Neurogenin-1; NGN-1; Neurogenic differentiation factor 3; Neurogenin-related protein 1; neurogenin 1

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

0.05 mg (Baculovirus)

0.05 mg (Mammalian-Cell)

Sox9a, Blocking Peptide

Sox9a Immunizing Peptide

(#MBS425129)

Gene Names:

sox9a; jef; wu:fj17b12; zgc:111921

Other Names:

SRY-box containing gene 9a; fj17b12; wu: fj17b12; zgc: 111921; jellyfish; Sox9a (zebrafish); transcription factor SOX-9; SRY (sex determining region Y)-box 9a

Host/Reactivities:

Reactivity: Zebrafish

RuvB-like 2 (ruvbl2), Recombinant Protein

Recombinant Danio rerio RuvB-like 2 (ruvbl2)

(#MBS1212231)

Gene Names:

ruvbl2; reptin; zreptin; wu:fi25f01

Other Names:

ruvB-like 2; RuvB-like AAA ATPase 2

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1610

$7475

Bone Morphogenetic Protein 4, ELISA Kit

Chicken Bone Morphogenetic Protein 4 ELISA Kit

(#MBS743592)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Chicken

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Protein naked cuticle homolog 1 (nkd1), Recombinant Protein

Recombinant Danio rerio Protein naked cuticle homolog 1 (nkd1)

(#MBS1328360)

Gene Names:

nkd1

Other Names:

protein naked cuticle homolog 1; naked cuticle homolog 1 (Drosophila)

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1590

$7425

LIM/homeobox protein Lhx1 (lhx1a), Recombinant Protein

Recombinant Danio rerio LIM/homeobox protein Lhx1 (lhx1a)

(#MBS1436035)

Gene Names:

lhx1a; LHX1; lim1; wu:fe25d04; wu:fj36b06

Other Names:

LIM/homeobox protein Lhx1; LIM homeobox 1a

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1550

$2930

$4305

$7375

Bone Morphogenetic Protein 4, ELISA Kit

Monkey Bone Morphogenetic Protein 4 ELISA Kit

(#MBS743097)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Monkey

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Zinc finger protein draculin (drl), Recombinant Protein

Recombinant Danio rerio Zinc finger protein draculin (drl)

(#MBS1482721)

Gene Names:

drl; dra; cb253; zgc:109857

Other Names:

zinc finger protein draculin; draculin

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1555

$2940

$4320

$7385

Egr-2b, Polyclonal Antibody

Egr-2b, ID (Early Growth Response 2b, egr2b, Dr.75080)

(#MBS643174)

Gene Names:

egr2b; egr2; cb427; krx20; KRX-20; krox20; zgc:92210; id:ibd5073; wu:fb71h10

Other Names:

Anti -Egr-2b; ID (Early Growth Response 2b; Dr.75080); early growth response protein 2b; early growth response 2b

Host/Reactivities:

Host: Rabbit

Purification:

Affinity PurifiedPurified by immunoaffinity chromatography.

Isotype/Clone:

Isotype: IgG

Applications:

ELISA (EL/EIA), Western Blot (WB)

Osteocalcin (bglap), Recombinant Protein

Recombinant Danio rerio Osteocalcin (bglap)

(#MBS1126314)

Gene Names:

bglap

Other Names:

Osteocalcin

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1160

1 mg (E-Coli)

$1335

$2365

$3260

$6765

Axin-1 (axin1), Recombinant Protein

Recombinant Danio rerio Axin-1 (axin1), partial

(#MBS1009657)

Gene Names:

axin1; wu:fi22e03; wu:fj14c08; wu:fk11b03; zgc:109872

Other Names:

axin-1; axin 1

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

Bone Morphogenetic Protein 4, ELISA Kit

Porcine Bone Morphogenetic Protein 4 ELISA Kit

(#MBS737504)

Gene Names:

BMP4; bmp-4; zbmp-4; zgc:100779

Other Names:

bone morphogenetic protein 4

Host/Reactivities:

Reactivity: Porcine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

100-2500pg/mL

Sensitivity

1.0pg/mL

Homeobox protein Hox-B1b (hoxb1b), Recombinant Protein

Recombinant Danio rerio Homeobox protein Hox-B1b (hoxb1b)

(#MBS1426814)

Gene Names:

hoxb1b; cb249; hoxa1; Hoxa-1; id:ibd5001

Other Names:

homeobox protein Hox-B1b; homeobox B1b

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1435

$2770

$4015

$7200

Protein Wnt-8b (wnt8b), Recombinant Protein

Recombinant Danio rerio Protein Wnt-8b (wnt8b)

(#MBS1173824)

Gene Names:

wnt8b; wnt-8b

Other Names:

Recombinant Protein Wnt-8b (wnt8b); Protein Wnt-8b; wingless-type MMTV integration site family; member 8b

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1260

Connexin 43, ELISA Kit

Sheep Connexin 43 ELISA Kit

(#MBS738240)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Sheep

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Connexin 43, ELISA Kit

Monkey Connexin 43 ELISA Kit

(#MBS737175)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Monkey

Assay Type

Sandwich

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Retinoic acid receptor gamma-A (rarga), Recombinant Protein

Recombinant Danio rerio Retinoic acid receptor gamma-A (rarga)

(#MBS1377875)

Gene Names:

rarga; rarg; NR1B3; rarg2; wu:fb01e02; wu:fb01f03; wu:fc35a09; etID33387.23; etID309710.23

Other Names:

retinoic acid receptor gamma-A; retinoic acid receptor gamma a

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1645

$7525

Connexin 43, ELISA Kit

Goat Connexin 43 ELISA Kit

(#MBS734961)

Gene Names:

CX43; gja1; cx43a1; zfCx43.3

Other Names:

Cx43 protein; connexin 43

Host/Reactivities:

Reactivity: Goat

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Homeobox protein OTX1 B (otx1b), Recombinant Protein

Recombinant Danio rerio Homeobox protein OTX1 B (otx1b)

(#MBS1432900)

Gene Names:

otx1b; otx1; cb769; zOtx1; fj99f05; wu:fj99f05

Other Names:

homeobox protein OTX1 B; orthodenticle homeobox 1

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1450

$2790

$4065

$7240

Protein jagged-1b (jag1b), Recombinant Protein

Recombinant Danio rerio Protein jagged-1b (jag1b), partial

(#MBS1346733)

Gene Names:

jag1b; kmi; puc; jag3; unp1069

Other Names:

Protein jagged-1b; jagged 1b

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

Sox9b, Blocking Peptide

Sox9b Immunizing Peptide

(#MBS427903)

Gene Names:

Sox9b; fb18d01; wu:fb18d01

Other Names:

SRY-box containing gene 9b; wu: fb18d01; Sox9b (zebrafish aa5-18); SRY (sex determining region Y)-box 9b

Host/Reactivities:

Reactivity: Zebrafish

Protein Wnt-2 (wnt2), Recombinant Protein

Recombinant Danio rerio Protein Wnt-2 (wnt2)

(#MBS1455353)

Gene Names:

wnt2; wnt-2; ZfWnt2

Other Names:

protein Wnt-2; wingless-type MMTV integration site family member 2

Host/Reactivities:

Host: E Coli or Yeast or Baculovirus or Mammalian Cell

Purity:

Greater or equal to 85% purity as determined by SDS-PAGE.

$1455

$2795

$4070

$7245