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DEFB3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619628

A novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, BD3) was isolated from human lesional psoriatic scales and cloned from keratinocytes. BD3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many… More details

$450 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BD3 (Defb3), Polyclonal Antibody
Full Product Name
BD3 (beta Defensin-3)
Product Gene Name
Product Synonym Names
Anti -BD3 (beta Defensin-3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes aa23-33, GIINTLQKYYC of human BD3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Molecular Weight
7,126 Da
Chromosome Location
Chromosome: 8; NC_000074.5 (19293361..19295339). Location: 8; 8
3D Structure
ModBase 3D Structure for Q9WTL0
Immunogen
5-kD human beta-defensin-3 protein.

Product Categories/Family for anti-Defb3 antibody

Applications Tested/Suitable for anti-Defb3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Defb3 antibody
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1:500-1:1000

Other Notes

Small volumes of anti-Defb3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Defb3 purchase

MBS619628 is an antibody targeting Defb3. Also known as BD3 (beta Defensin-3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Defb3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-defensin 3
NCBI Official Synonym Full Names
defensin beta 3
NCBI Official Symbol
Defb3
NCBI Official Synonym Symbols
BD-3; MGC129397
UniProt Protein Name
Beta-defensin 3
UniProt Synonym Protein Names
Defensin, beta 3
Protein Family
UniProt Gene Name
Defb3
UniProt Synonym Gene Names
Bd3
UniProt Entry Name
DEFB3_MOUSE
NCBI Protein Information
beta-defensin 3; OTTMUSP00000022575

UniProt Comments for Defb3

Function: Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa. Ref.1

Subcellular location: Secreted.

Tissue specificity: Highest expression in salivary glands, epididymis, ovary and pancreas and to a lesser extent in lung, liver and brain. Low or no expression in skeletal muscle and tongue. Ref.1 Ref.3

Induction: By bacterial infection. Ref.1

Sequence similarities: Belongs to the beta-defensin family. LAP/TAP subfamily.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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