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HAS3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249552

HAS3 Antibody, Hyaluronan synthase 3 Antibody, Hyaluronate synthase 3 Antibody, HA synthase 3 Antibody, Hyaluronic acid synthase 3 Antibody Description: Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it… More details

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Product Overview

Online Datasheet in PDF
Product Name
HAS3, Polyclonal Antibody
Full Product Name
Anti-HAS3 Antibody (aa137-164) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal to Human HAS3; Human HAS3; Hyaluronan synthase 3; Hyaluronate synthase 3; HA synthase 3; Hyaluronic acid synthase 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human (Predicted: Mouse)
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Protein A purified
Concentration
0.5 mg/ml (lot specific)
Specificity
This HAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human HAS3.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.
OMIM
602428
3D Structure
ModBase 3D Structure for O00219
Immunogen Species
HAS3 antibody was raised against Human
Antigen Modification
aa137-164
Target
HAS3
Applications Tested/Suitable for anti-HAS3 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-HAS3 antibody
IHC-P (1:100)
WB (1:1000)
Optimal dilutions to be determined by the researcher.

Immunohistochemistry (IHC) of anti-HAS3 antibody

Anti-HAS3 antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-HAS3 Polyclonal Antibody – Cat# MBS249552

Immunohistochemistry (IHC) of anti-HAS3 antibody

Anti-HAS3 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Rabbit Anti-HAS3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249552

Western Blot (WB) of anti-HAS3 antibody

HAS3 Antibody western blot of A549 cell line lysates (35 ug/lane). The HAS3 antibody detected the HAS3 protein (arrow).
Rabbit Anti-HAS3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249552

Other Notes

Small volumes of anti-HAS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAS3 purchase

MBS249552 is an antibody targeting HAS3. Also known as Anti-HAS3 Antibody (aa137-164) IHC-plus. Reactive in Human (Predicted: Mouse). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HAS3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hyaluronan synthase 3 isoform a
NCBI Official Synonym Full Names
hyaluronan synthase 3
NCBI Official Symbol
HAS3
UniProt Protein Name
Hyaluronan synthase 3
UniProt Synonym Protein Names
Hyaluronate synthase 3; Hyaluronic acid synthase 3; HA synthase 3
Protein Family
UniProt Gene Name
HAS3
UniProt Synonym Gene Names
HA synthase 3
UniProt Entry Name
HYAS3_HUMAN
NCBI Protein Information
hyaluronan synthase 3

NCBI Summary for HAS3

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
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UniProt Comments for HAS3

HAS3: Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. Belongs to the NodC/HAS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; Membrane protein, multi-pass; EC 2.4.1.212; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: hyaluronan synthase activity

Biological Process: carbohydrate metabolic process; cell adhesion; extracellular polysaccharide biosynthetic process; glycosaminoglycan metabolic process; hyaluronan biosynthetic process; hyaluronan metabolic process; positive regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HAS3 antibody

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