• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

HGD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7044135

MBS7044135 is an antibody targeting HGD. Also known as HGD Antibody. Reactive in Human. Host: Rabbit. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HGD, Polyclonal Antibody
Full Product Name
HGD Antibody
Product Gene Name
Product Synonym Names
Homogentisate 1; 2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; HGD; HGO
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
OMIM
203500
3D Structure
ModBase 3D Structure for Q93099
Species
Human
Immunogen
Recombinant human Homogentisate 1,2-dioxygenase protein (226-445AA)
Immunogen Species
Homo sapiens (Human)
Research Area
Signal Transduction
Target Names
HGD
Conjugate
Non-conjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HGD antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-HGD antibody
WB: 1:1000-1:5000
IHC: 1:20-1:200

Western Blot (WB) of anti-HGD antibody

Western blot
All lanes:  HGDantibody at 2.43ug/ml
Lane 1 : Hela whole cell lysate
Lane 2 : 293T whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa
Rabbit Anti-HGD Polyclonal Antibody – Cat# MBS7044135

Immunohistochemistry (IHC) of anti-HGD antibody

Immunohistochemistry of paraffin-embedded human liver tissue using MBS7044135 at dilution 1:100
Rabbit Anti-HGD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7044135

Immunohistochemistry (IHC) of anti-HGD antibody

Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7044135 at dilution 1:100
Rabbit Anti-HGD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7044135

Other Notes

Small volumes of anti-HGD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HGD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homogentisate 1,2-dioxygenase
NCBI Official Synonym Full Names
homogentisate 1,2-dioxygenase
NCBI Official Symbol
HGD
NCBI Official Synonym Symbols
AKU; HGO
UniProt Protein Name
Homogentisate 1,2-dioxygenase
UniProt Synonym Protein Names
Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase
UniProt Gene Name
HGD
UniProt Synonym Gene Names
HGO
UniProt Entry Name
HGD_HUMAN
NCBI Protein Information
homogentisate 1,2-dioxygenase

NCBI Summary for HGD

This gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.[provided by RefSeq, May 2010]

UniProt Comments for HGD

HGD: Defects in HGD are the cause of alkaptonuria (AKU). AKU is an autosomal recessive error of metabolism characterized by an increase in the level of homogentisic acid. The clinical manifestations of AKU are urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues, and spine arthritis. Belongs to the homogentisate dioxygenase family.

Protein type: EC 1.13.11.5; Amino Acid Metabolism - tyrosine; Oxidoreductase

Chromosomal Location of Human Ortholog: 3q13.33

Cellular Component: cytosol

Molecular Function: homogentisate 1,2-dioxygenase activity; protein binding

Biological Process: L-phenylalanine catabolic process

Disease: Alkaptonuria
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HGD antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000