• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-STAT2 antibody :: Rabbit anti-Human STAT2 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS416913
Unit / Price
  0.1 mg  /  $405 +1 FREE 8GB USB
Testing Data
Product Name

STAT2, Polyclonal Antibody

Popular Item
Also Known As

Anti-STAT2 Antibody

Product Synonym Names
Anti-Stat2 (Ab-690) Antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
851
OMIM
600556
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Stat2 (Ab-690) Antibody detects endogenous levels of total Stat2 protein.
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (lot specific)
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg< sup>2< /sup>+and Ca< sup>2< /sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antibody was produced against synthesized non-phosphopeptide derived from human stat2 around the phosphorylation site of tyrosine 690 (R-K-YP-L-K).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Other Notes
Small volumes of anti-STAT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-STAT2 antibody
This gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Applications Tested/Suitable for anti-STAT2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-STAT2 antibody
WB: 1:500~1:1000
IHC:1:50~1:100

Testing Data of anti-STAT2 antibody
anti-STAT2 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for STAT2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
97,457 Da
NCBI Official Full Name
Stat2
NCBI Official Synonym Full Names
signal transducer and activator of transcription 2, 113kDa
NCBI Official Symbol
STAT2  [Similar Products]
NCBI Official Synonym Symbols
P113; ISGF-3; STAT113
  [Similar Products]
NCBI Protein Information
signal transducer and activator of transcription 2; interferon alpha induced transcriptional activator; signal transducer and activator of transcription 2, 113kD
UniProt Protein Name
Signal transducer and activator of transcription 2
UniProt Synonym Protein Names
p113
UniProt Gene Name
STAT2  [Similar Products]
UniProt Entry Name
STAT2_HUMAN
NCBI Summary for STAT2
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
UniProt Comments for STAT2
STAT2: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Binds to the IFN-stimulated response element (ISRE) and to the Gas element. This multiprotein transcription factor is termed ISGF3. Two alternatively spliced isoforms have been described.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol

Molecular Function: identical protein binding; protein binding; signal transducer activity; DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral reproduction; cytokine and chemokine mediated signaling pathway; JAK-STAT cascade; defense response to virus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000