Rabbit Anti-HMOX2 Polyclonal Antibody – Cat# MBS127414

Western blot analysis of extracts of various cell lines, using HMOX2 antibody at 1:400 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.

HMOX2 Antibody – Rabbit Polyclonal

Name: HMOX2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS127414
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS127414

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HMOX2, Polyclonal Antibody

Full Product Name

HMOX2 Polyclonal Antibody

Product Gene Name

anti-HMOX2 antibody

Product Synonym Names

HO-2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Preparation and Storage

Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated Molecular Weight: 32kDa/36kDa
Observed Molecular Weight: 36kDa

OMIM

141251

3D Structure

ModBase 3D Structure for P30519

Species

Human

Immunogen

Recombinant protein of human HMOX2

Product Categories/Family for anti-HMOX2 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-HMOX2 antibody

Western Blot (WB)

Application Notes for anti-HMOX2 antibody

WB: 1:500 - 1:1000

Other Notes

Small volumes of anti-HMOX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HMOX2 purchase

MBS127414 is an antibody targeting HMOX2. Also known as HMOX2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HMOX2. It may not necessarily be applicable to this product.

NCBI GI #

1170328

NCBI GeneID

3163

NCBI Accession #

P30519.2

UniProt Primary Accession #

P30519

UniProt Secondary Accession #

O60605; A8MT35; D3DUD5; I3L430

UniProt Related Accession #

P30519

NCBI Official Full Name

Heme oxygenase 2

NCBI Official Synonym Full Names

heme oxygenase (decycling) 2

NCBI Official Symbol

HMOX2

NCBI Official Synonym Symbols

HO-2

UniProt Protein Name

Heme oxygenase 2

UniProt Gene Name

HMOX2

UniProt Synonym Gene Names

HO2; HO-2

UniProt Entry Name

HMOX2_HUMAN

NCBI Protein Information

heme oxygenase 2

UniProt Comments for HMOX2

HMOX2: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter. Belongs to the heme oxygenase family.

Protein type: EC 1.14.99.3; Oxidoreductase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: endoplasmic reticulum membrane; membrane; plasma membrane

Molecular Function: protein binding; metal ion binding; heme oxygenase (decyclizing) activity

Biological Process: cellular iron ion homeostasis; heme catabolic process; porphyrin metabolic process; response to hypoxia; heme oxidation; transmembrane transport

Research Articles on HMOX2

1. We believe that a dysfunctional HO-ferritin system leads to increased levels of proinflammatory mediators, thus contributing to the inflammation characteristic of pterygia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HMOX2 antibody

Reference Product	PubMed Publications
BLVRA antibody	>1 publications with HMOX2 and BLVRA

Pathways associated with anti-HMOX2 antibody

Products by Pathway	Pathway Diagram
Heme Degradation Pathway antibodies	Heme Degradation Pathway Diagram
Iron Uptake And Transport Pathway antibodies	Iron Uptake And Transport Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Porphyrins Pathway antibodies	Metabolism Of Porphyrins Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Porphyrin And Chlorophyll Metabolism Pathway antibodies	Porphyrin And Chlorophyll Metabolism Pathway Diagram
Porphyrin And Chlorophyll Metabolism Pathway antibodies	Porphyrin And Chlorophyll Metabolism Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Heme Degradation Pathway antibodies	Heme Degradation Pathway Diagram

Diseases associated with anti-HMOX2 antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>2 publications with HMOX2 and Brain Diseases
Nervous System Diseases Antibodies	>2 publications with HMOX2 and Nervous System Diseases
Inflammation Antibodies	>2 publications with HMOX2 and Inflammation
Necrosis Antibodies	>2 publications with HMOX2 and Necrosis
Pain Antibodies	>1 publications with HMOX2 and Pain
Cardiovascular Diseases Antibodies	>1 publications with HMOX2 and Cardiovascular Diseases
Hypertension Antibodies	>1 publications with HMOX2 and Hypertension
Fatty Liver Antibodies	>1 publications with HMOX2 and Fatty Liver
Liver Diseases Antibodies	>1 publications with HMOX2 and Liver Diseases

Organs/Tissues associated with anti-HMOX2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with HMOX2 and Blood
Liver Antibodies	>3 publications with HMOX2 and Liver
Ear Antibodies	>1 publications with HMOX2 and Ear
Muscle Antibodies	>1 publications with HMOX2 and Muscle
Eye Antibodies	>1 publications with HMOX2 and Eye
Skin Antibodies	>1 publications with HMOX2 and Skin
Testis Antibodies	>1 publications with HMOX2 and Testis
Brain Antibodies	>1 publications with HMOX2 and Brain