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MEOX1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7045298

Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994).… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MEOX1, Polyclonal Antibody
Full Product Name
MEOX1 Antibody
Product Gene Name
anti-MEOX1 antibody
Product Synonym Names
Homeobox protein MOX-1 antibody; MEOX1 antibody; MEOX1_HUMAN antibody; Mesenchyme homeo box 1 antibody; Mesenchyme homeobox 1 antibody; MOX 1 antibody; MOX1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze
OMIM
214300
3D Structure
ModBase 3D Structure for P50221
Immunogen
Recombinant Human Homeobox protein MOX-1 protein (1-254AA)
Conjugate
Non-conjugated
Species
Homo sapiens (Human)
Research Area
Cell Biology
Target Names
MEOX1
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MEOX1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-MEOX1 antibody
IHC:1:20-1:200

Western Blot (WB) of anti-MEOX1 antibody

Western blot
All lanes: MEOX1 antibody at 3.43ug/ml
Lane 1 : Mouse liver tissue
Lane 2 : Mouse lung tissue
Lane 3 : Mouse kidney tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 28,20,16 kDa
Observed band size: 28,90 kDa
Rabbit Anti-MEOX1 Polyclonal Antibody – Cat# MBS7045298

Immunohistochemistry (IHC) of anti-MEOX1 antibody

Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS7045298 at dilution 1:100
Rabbit Anti-MEOX1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7045298

Immunohistochemistry (IHC) of anti-MEOX1 antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7045298 at dilution 1:100
Rabbit Anti-MEOX1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7045298

Other Notes

Small volumes of anti-MEOX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MEOX1 purchase

MBS7045298 is an antibody targeting MEOX1. Also known as MEOX1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MEOX1. It may not necessarily be applicable to this product.

NCBI GI #
91208415
NCBI GeneID
4222
NCBI Accession #
NP_001035091.1
UniProt Primary Accession #
P50221
UniProt Secondary Accession #
Q15069; A8K524; A8MWF9
UniProt Related Accession #
P50221
GenBank Nucleotide #
NM_001040002.1
NCBI Official Full Name
homeobox protein MOX-1 isoform 3
NCBI Official Synonym Full Names
mesenchyme homeobox 1
NCBI Official Symbol
MEOX1
NCBI Official Synonym Symbols
KFS2; MOX1
UniProt Protein Name
Homeobox protein MOX-1
UniProt Synonym Protein Names
Mesenchyme homeobox 1
Protein Family
Homeobox protein
UniProt Gene Name
MEOX1
UniProt Synonym Gene Names
MOX1
UniProt Entry Name
MEOX1_HUMAN
NCBI Protein Information
homeobox protein MOX-1

NCBI Summary for MEOX1

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for MEOX1

MEOX1: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: multicellular organismal development

Disease: Klippel-feil Syndrome 2, Autosomal Recessive
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Research Articles on MEOX1

1. The G > A p.Q84X mutation in the MEOX1 is identified in Klippel-Feil syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-MEOX1 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with MEOX1 and Congenital Abnormalities
 Fibrosis Antibodies  >2 publications with MEOX1 and Fibrosis
 Embryo Loss Antibodies  >2 publications with MEOX1 and Embryo Loss
 Cardiovascular Diseases Antibodies  >1 publications with MEOX1 and Cardiovascular Diseases
 Abnormalities, Multiple Antibodies  >1 publications with MEOX1 and Abnormalities, Multiple
 Neurobehavioral Manifestations Antibodies  >1 publications with MEOX1 and Neurobehavioral Manifestations
 Breast Neoplasms Antibodies  >1 publications with MEOX1 and Breast Neoplasms
 Learning Disorders Antibodies  >1 publications with MEOX1 and Learning Disorders

Organs/Tissues associated with anti-MEOX1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >20 publications with MEOX1 and Muscle
 Embryonic Tissue Antibodies  >15 publications with MEOX1 and Embryonic Tissue
 Heart Antibodies  >8 publications with MEOX1 and Heart
 Vascular Antibodies  >5 publications with MEOX1 and Vascular
 Blood Antibodies  >3 publications with MEOX1 and Blood
 Connective Tissue Antibodies  >3 publications with MEOX1 and Connective Tissue
 Skin Antibodies  >3 publications with MEOX1 and Skin
 Lung Antibodies  >1 publications with MEOX1 and Lung
 Kidney Antibodies  >1 publications with MEOX1 and Kidney
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