Il-1 BETA (IL1B) Antibody – Rabbit Polyclonal

Polyclonal

IgG

Rabbit

Preservative Free
Purified IgG - liquid

IgG concentration 0.5 mg/ml (lot specific)

This item recognizes chicken Interleukin 1 beta (chIL-1beta), which shares
homology with mammalian IL-1beta.

IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression.

Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.

This item neutralizes chicken IL-1 beta (1-2).

Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Recombinant chicken IL-1beta
Buffer Solution||Phosphate buffered saline

Antisera to chicken Interleukin-1beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G.

Chicken