Rabbit Anti-GZMK Polyclonal Antibody – Cat# MBS2092994

Granzyme K (GZMK) Antibody – Rabbit Polyclonal

Name: GZMK Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2092994
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2092994

MBS2092994 is an antibody targeting GZMK. Also known as Biotin-Linked Polyclonal Antibody to Granzyme K (GZMK). Reactive in Mus musculus (Mouse). Host: Rabbit. More details

$220 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Granzyme K (GZMK), Polyclonal Antibody

Full Product Name

Biotin-Linked Polyclonal Antibody to Granzyme K (GZMK)

Product Gene Name

anti-GZMK antibody

Product Synonym Names

GZM-K; TRYP2; PRSS; Serine Protease,Granzyme 3; Tryptase II; Fragmentin-3; Granzyme-3; NK-tryptase-2

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Mus musculus (Mouse)

Form/Format

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Purity/Purification

Antigen-specific Affinity Chromatography.

Concentration

0.29mg/mL (lot specific)

Preparation and Storage

Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Matching Pairs

Unconjugated Antibody: GZMK (MBS2027859)
Biotin Conjugated Antibody: GZMK (MBS2092994)

Matching Pairs

Biotin Conjugated Antibody: GZMK (MBS2092994)
Immunogen: GZMK (MBS2029386)

OMIM

U35237 mRNA

3D Structure

ModBase 3D Structure for P49863

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Source

Antibody labeling

Label

Biotin

Unconjugated Antibody

MBS2027859

Traits

Liquid

Immunogen

Recombinant GZMK (Gln44~Val227) expressed in E.coli (MBS2029386).

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-GZMK antibody

Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunofluorescence (IF)

Application Notes for anti-GZMK antibody

Western blotting: 0.5-2ug/mL;
Immunohistochemistry: 5-20ug/mL;
Immunocytochemistry: 5-20ug/mL;
Optimal working dilutions must be determined by end user.

Other Notes

Small volumes of anti-GZMK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GZMK. It may not necessarily be applicable to this product.

NCBI GI #

4504235

NCBI GeneID

3003

NCBI Accession #

NP_002095.1

UniProt Primary Accession #

P49863

UniProt Secondary Accession #

B2R563

GenBank Nucleotide #

NM_002104.2

NCBI Official Full Name

granzyme K

UniProt Protein Name

Granzyme K

UniProt Synonym Protein Names

Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2

Protein Family

Granzyme

UniProt Gene Name

GZMK

UniProt Synonym Gene Names

TRYP2; NK-Tryp-2

UniProt Comments for GZMK

GZMK: this protein is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]

Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: proteolysis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-GZMK antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>4 publications with GZMK and Immune System Diseases
Inflammation Antibodies	>4 publications with GZMK and Inflammation
Heart Diseases Antibodies	>1 publications with GZMK and Heart Diseases
Depressive Disorder Antibodies	>1 publications with GZMK and Depressive Disorder
Necrosis Antibodies	>1 publications with GZMK and Necrosis

Organs/Tissues associated with anti-GZMK antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>24 publications with GZMK and Blood
Lung Antibodies	>3 publications with GZMK and Lung
Brain Antibodies	>1 publications with GZMK and Brain
Thymus Antibodies	>1 publications with GZMK and Thymus