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Plexin B1 (PLXNB1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2027585
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2027585 is an antibody targeting PLXNB1. Also known as Polyclonal Antibody to Plexin B1 (PLXNB1). Reactive in Mouse. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Plexin B1 (PLXNB1), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Plexin B1 (PLXNB1)
Product Gene Name
anti-PLXNB1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid
Purity/Purification
Affinity Chromatography
Concentration
0.93mg/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against PLXNB1. It has beenselected for its ability to recognize PLXNB1 in immunohistochemical staining andwestern blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Matching Pairs
Unconjugated Antibody: PLXNB1 (MBS2027585)
Immunogen: PLXNB1 (MBS2029252)
Matching Pairs
Unconjugated Antibody: PLXNB1 (MBS2027585)
APC-CY7 Conjugated Antibody: PLXNB1 (MBS2079694)
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Molecular Weight
231,376 Da
3D Structure
ModBase 3D Structure for Q8CJH3
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Fragment
PLXNB1 (Leu1598~Val1849)
Organism Species
Mus musculus (Mouse)
Cross Reactivity
Mouse
Conjugate
No Conjugate
Immunogen
Recombinant PLXNB1 (Leu1598~Val1849) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2079696
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PLXNB1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-PLXNB1 antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-PLXNB1 antibody

Western Blot: Sample: Recombinant protein.
Rabbit Anti-PLXNB1 Polyclonal Antibody – Cat# MBS2027585

Immunohistochemistry (IHC) of anti-PLXNB1 antibody

DAB staining on fromalin fixed paraffin- embedded Kidney tissue)
Rabbit Anti-PLXNB1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2027585

Immunohistochemistry (IHC) of anti-PLXNB1 antibody

DAB staining on IHC-P; Samples: Mouse Kidney Tissue)
Rabbit Anti-PLXNB1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2027585

Other Notes

Small volumes of anti-PLXNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLXNB1. It may not necessarily be applicable to this product.

NCBI GI #
225690610
NCBI GeneID
235611
NCBI Accession #
NP_766363.2
UniProt Primary Accession #
Q8CJH3
UniProt Secondary Accession #
Q6ZQC3; Q80ZZ1; E9QKS4
UniProt Related Accession #
Q8CJH3
GenBank Nucleotide #
NM_172775.2
NCBI Official Full Name
plexin-B1
NCBI Official Synonym Full Names
plexin B1
NCBI Official Symbol
Plxnb1
NCBI Official Synonym Symbols
AU042020; mKIAA0407; 2900002G15Rik
UniProt Protein Name
Plexin-B1
Protein Family
Plexin
UniProt Gene Name
Plxnb1
UniProt Synonym Gene Names
Kiaa0407
NCBI Protein Information
plexin-B1

UniProt Comments for PLXNB1

PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.

Chromosomal Location of Human Ortholog: 9|9 F2

Cellular Component: integral component of membrane; integral component of plasma membrane; membrane; plasma membrane

Molecular Function: GTPase activating protein binding; protein binding; semaphorin receptor activity

Biological Process: axon extension; negative regulation of cell adhesion; negative regulation of osteoblast proliferation; neuron projection morphogenesis; positive regulation of axonogenesis; positive regulation of GTPase activity; positive regulation of phosphoinositide 3-kinase cascade; regulation of cell shape; regulation of cytoskeleton organization; signal transduction
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Research Articles on PLXNB1

1. Plexin-B1 and -B2 play redundant or compensatory roles during forebrain development to ensure proper neuronal production and neocortical expansion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLXNB1 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Sema4D In Semaphorin Signaling Pathway antibodies  Sema4D In Semaphorin Signaling Pathway Diagram
 Sema4D Induced Cell Migration And Growth-cone Collapse Pathway antibodies  Sema4D Induced Cell Migration And Growth-cone Collapse Pathway Diagram
 Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway antibodies  Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram

Diseases associated with anti-PLXNB1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >26 publications with PLXNB1 and Neoplasms
 Metaplasia Antibodies  >8 publications with PLXNB1 and Metaplasia
 Breast Neoplasms Antibodies  >5 publications with PLXNB1 and Breast Neoplasms
 Brain Diseases Antibodies  >3 publications with PLXNB1 and Brain Diseases
 Kidney Neoplasms Antibodies  >2 publications with PLXNB1 and Kidney Neoplasms
 Necrosis Antibodies  >2 publications with PLXNB1 and Necrosis
 Prostatic Diseases Antibodies  >2 publications with PLXNB1 and Prostatic Diseases
 Genital Diseases, Male Antibodies  >2 publications with PLXNB1 and Genital Diseases, Male
 Kidney Diseases Antibodies  >2 publications with PLXNB1 and Kidney Diseases
 Cardiovascular Diseases Antibodies  >2 publications with PLXNB1 and Cardiovascular Diseases

Organs/Tissues associated with anti-PLXNB1 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >16 publications with PLXNB1 and Embryonic Tissue
 Brain Antibodies  >13 publications with PLXNB1 and Brain
 Kidney Antibodies  >9 publications with PLXNB1 and Kidney
 Bone Antibodies  >7 publications with PLXNB1 and Bone
 Lung Antibodies  >4 publications with PLXNB1 and Lung
 Skin Antibodies  >4 publications with PLXNB1 and Skin
 Liver Antibodies  >2 publications with PLXNB1 and Liver
 Eye Antibodies  >2 publications with PLXNB1 and Eye
 Dorsal Root Ganglion Antibodies  >1 publications with PLXNB1 and Dorsal Root Ganglion
 Pancreas Antibodies  >1 publications with PLXNB1 and Pancreas
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