PGC Recombinant Protein – Cat# MBS2009827

Pepsinogen C (PGC) Recombinant Protein

Name: PGC Recombinant Protein; Pepsinogen C; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS2009827
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2009827

MBS2009827 is a recombinant protein targeting PGC. Also known as Recombinant Pepsinogen C (PGC). Host: E Coli. More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pepsinogen C (PGC), Recombinant Protein

Full Product Name

Recombinant Pepsinogen C (PGC)

Product Gene Name

PGC recombinant protein

Sequence

The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-SLLR VPLRKMKSIR ETMKEQGVLK DFLKTHKYDP GQKYHFGNFG DYSVLYEPMA YMDASYFGEI SIGTPPQNFL VLFDTGSSNL WVSSVYCQSE ACTTHARFNP SKSSTYYTEG QTFSLQYGTG SLTGFFGYDT LTVQSIQVPN QEFGLSENEP GTNFVYAQFD GIMGLAYPGL SSGGATTALQ GMLGEGALSQ PLFGVYLGSQ QGSNGGQIVF GGVDKNLYTG EITWVPVTQE LYWQITIDDF LIGDQASGWC SSQGCQGIVD TGTSLLVMPA QYLSELLQTI GAQEGEYGEY FVSCDSVSSL PTLSFVLNGV QFPLSPSSYI IQEDNFCMVG LESISLTSES GQPLWILGDV FLRSYYAIFD MGNNKVGLAT SV

Host

E Coli

Form/Format

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

Purity/Purification

> 95%

Preparation and Storage

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Matching Pairs

Unconjugated Antibody: PGC (MBS2001428)
Immunogen: PGC (MBS2009827)

Matching Pairs

Biotin Conjugated Antibody: PGC (MBS2006252)
Immunogen: PGC (MBS2009827)

Molecular Weight

42.5kDa

Chromosome Location

Chromosome: 9; NC_005108.3 (14191145..14199127, complement). Location: 9q12

3D Structure

ModBase 3D Structure for P04073

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Organism

Rattus norvegicus (Rat)

Expression System

Prokaryotic expression

Residues

Ser17~Val392 (Accession # P04073) with N-terminal His-Tag

Endotoxin Level

<1.0EU per 1ug (determined by the LAL method)

Reconstitution

Reconstitute in sterile PBS, pH7.2-pH7.4.

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for PGC recombinant protein

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Other Notes

Small volumes of PGC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PGC. It may not necessarily be applicable to this product.

NCBI GI #

18959216

NCBI GeneID

24864

NCBI Accession #

NP_579818.1

UniProt Primary Accession #

P04073

UniProt Related Accession #

P04073

GenBank Nucleotide #

NM_133284.2

NCBI Official Full Name

gastricsin

NCBI Official Synonym Full Names

progastricsin (pepsinogen C)

NCBI Official Symbol

Pgc

NCBI Official Synonym Symbols

PG1; Pg-1; Upg1

UniProt Protein Name

Gastricsin

UniProt Synonym Protein Names

Pepsinogen C

Protein Family

Gastricsin

UniProt Gene Name

Pgc

UniProt Entry Name

PEPC_RAT

NCBI Protein Information

gastricsin; Urinary pepsinogen 1

NCBI Summary for PGC

inactive precursor of pepsin; member of aspartic proteinases [RGD, Feb 2006]

UniProt Comments for PGC

PGC: Hydrolyzes a variety of proteins. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Secreted, signal peptide; EC 3.4.23.3; Secreted

Molecular Function: aspartic-type endopeptidase activity

Biological Process: digestion; proteolysis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PGC recombinant protein

Reference Product	PubMed Publications
Pck1 recombinant protein	>9 publications with PGC and Pck1
Pde2a recombinant protein	>3 publications with PGC and Pde2a
Pde5a recombinant protein	>1 publications with PGC and Pde5a
Pck2 recombinant protein	>1 publications with PGC and Pck2

Diseases associated with PGC recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>226 publications with PGC and Nervous System Diseases
Cardiovascular Diseases Antibodies	>219 publications with PGC and Cardiovascular Diseases
Neoplasms Antibodies	>203 publications with PGC and Neoplasms
Fatty Liver Antibodies	>167 publications with PGC and Fatty Liver
Inflammation Antibodies	>167 publications with PGC and Inflammation
Liver Diseases Antibodies	>115 publications with PGC and Liver Diseases
Hypertrophy Antibodies	>96 publications with PGC and Hypertrophy
Necrosis Antibodies	>94 publications with PGC and Necrosis
Kidney Diseases Antibodies	>74 publications with PGC and Kidney Diseases
Movement Disorders Antibodies	>61 publications with PGC and Movement Disorders

Organs/Tissues associated with PGC recombinant protein

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>6 publications with PGC and Placenta
Inner Ear Antibodies	>3 publications with PGC and Inner Ear