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GMDS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9419382

MBS9419382 is an antibody targeting GMDS. Also known as GMDS Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GMDS, Polyclonal Antibody
Full Product Name
GMDS Antibody
Product Gene Name
Product Synonym Names
GMDS; GDP-D-mannose dehydratase; GDP-mannose 4;6 dehydratase; GDP-mannose 4;6-dehydratase; GMD; SDR3E1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Specificity
GMDS Antibody detects endogenous levels of total GMDS
Preparation and Storage
Store at -20 degree C
Molecular Weight
39,054 Da
OMIM
AF042377 mRNA
3D Structure
ModBase 3D Structure for O60547
Immunogen
A synthesized peptide derived from human GMDS
Immunogen Type
Peptide

Product Categories/Family for anti-GMDS antibody

Applications Tested/Suitable for anti-GMDS antibody
Western Blot (WB)
Application Notes for anti-GMDS antibody
Western Blot: 1:1000-3000

Western Blot (WB) of anti-GMDS antibody

Western blot analysis GMDS using COLO205 whole cell lysates
Rabbit Anti-GMDS Polyclonal Antibody – Cat# MBS9419382

Other Notes

Small volumes of anti-GMDS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GMDS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GDP-mannose 4,6 dehydratase isoform 2
NCBI Official Synonym Full Names
GDP-mannose 4,6-dehydratase
NCBI Official Symbol
GMDS
NCBI Official Synonym Symbols
GMD; SDR3E1
UniProt Protein Name
GDP-mannose 4,6 dehydratase
UniProt Synonym Protein Names
GDP-D-mannose dehydratase; GMD
UniProt Gene Name
GMDS
UniProt Synonym Gene Names
GMD
UniProt Entry Name
GMDS_HUMAN
NCBI Protein Information
GDP-mannose 4,6 dehydratase

NCBI Summary for GMDS

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009]
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UniProt Comments for GMDS

GMD: an enzyme that converts GDP-D-mannose to GDP-4-keto-6-D- deoxymannose. Perticipates in the extravasation of activated lymphocytes.

Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 4.2.1.47; Lyase

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: cytoplasm; cytosol

Molecular Function: GDP-mannose 4,6-dehydratase activity; identical protein binding; protein binding

Biological Process: 'de novo' GDP-L-fucose biosynthetic process; GDP-mannose metabolic process; Notch signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GMDS antibody

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