Stromelysin-1 (ST1) ELISA Kit for Fish

Name: Fish ST1 ELISA Kit; Stromelysin-1; MyBioSource
Brand: MyBioSource
SKU: MBS035953
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS035953

MBS035953 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Stromelysin-1 (ST1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Product Name

Stromelysin-1 (ST1), ELISA Kit

Full Product Name

Fish Stromelysin-1 ELISA Kit

Product Gene Name

ST1 elisa kit

Species Reactivity

Fish

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

53,977 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (102706528..102714342, complement). Location: 11q22.3

OMIM

185250

3D Structure

ModBase 3D Structure for P08254

Other Notes

Small volumes of ST1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ST1. It may not necessarily be applicable to this product.

NCBI GI #

4505217

NCBI GeneID

4314

NCBI Accession #

NP_002413.1

UniProt Primary Accession #

P08254

UniProt Secondary Accession #

Q3B7S0; Q6GRF8; B2R8B8

UniProt Related Accession #

P08254

GenBank Nucleotide #

NM_002422.3

NCBI Official Full Name

stromelysin-1 preproprotein

NCBI Official Synonym Full Names

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

NCBI Official Symbol

MMP3

NCBI Official Synonym Symbols

SL-1; STMY; STR1; CHDS6; MMP-3; STMY1

UniProt Protein Name

Stromelysin-1

UniProt Synonym Protein Names

Matrix metalloproteinase-3; MMP-3; Transin-1

Protein Family

High affinity sulfate transporter

UniProt Gene Name

MMP3

UniProt Synonym Gene Names

STMY1; SL-1; MMP-3

UniProt Entry Name

MMP3_HUMAN

NCBI Protein Information

stromelysin-1; transin-1; proteoglycanase; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, progelatinase)

NCBI Summary for ST1

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

UniProt Comments for ST1

MMP3: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. Defects in MMP3 are the cause of susceptibility to coronary heart disease type 6 (CHDS6). A multifactorial disease characterized by an imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow. Decreased capacity of the coronary vessels is often associated with thickening and loss of elasticity of the coronary arteries. A polymorphism in the MMP3 promoter region is associated with the risk of coronary heart disease and myocardial infarction, due to lower MMP3 proteolytic activity and higher extracellular matrix deposition in atherosclerotic lesions. Belongs to the peptidase M10A family.

Protein type: EC 3.4.24.17; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: proteinaceous extracellular matrix; extracellular space; mitochondrion; extracellular region; cytosol

Molecular Function: zinc ion binding; metalloendopeptidase activity; endopeptidase activity; calcium ion binding

Biological Process: positive regulation of protein oligomerization; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; negative regulation of protein kinase B signaling cascade; protein catabolic process; proteolysis; regulation of cell migration

Disease: Coronary Heart Disease, Susceptibility To, 6

Research Articles on ST1

1. MMP-3 expression is induced by IL-1 and inhibited by IL-4 in MG-63 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ST1 elisa kit

Reference Product	PubMed Publications
MMP1 elisa kit	>216 publications with ST1 and MMP1
TIMP1 elisa kit	>60 publications with ST1 and TIMP1
IL1B elisa kit	>7 publications with ST1 and IL1B
EGFR elisa kit	>5 publications with ST1 and EGFR
CTNNB1 elisa kit	>4 publications with ST1 and CTNNB1
COL18A1 elisa kit	>2 publications with ST1 and COL18A1
PLG elisa kit	>2 publications with ST1 and PLG
BDNF elisa kit	>1 publications with ST1 and BDNF

Pathways associated with ST1 elisa kit

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies	Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
Collagen Formation Pathway antibodies	Collagen Formation Pathway Diagram
Degradation Of Collagen Pathway antibodies	Degradation Of Collagen Pathway Diagram
Degradation Of Collagen Pathway antibodies	Degradation Of Collagen Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
EGFR Transactivation By Gastrin Pathway antibodies	EGFR Transactivation By Gastrin Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram

Diseases associated with ST1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>128 publications with ST1 and Neoplasms
Inflammation Antibodies	>118 publications with ST1 and Inflammation
Cardiovascular Diseases Antibodies	>82 publications with ST1 and Cardiovascular Diseases
Necrosis Antibodies	>68 publications with ST1 and Necrosis
Nervous System Diseases Antibodies	>57 publications with ST1 and Nervous System Diseases
Heart Diseases Antibodies	>41 publications with ST1 and Heart Diseases
Atherosclerosis Antibodies	>37 publications with ST1 and Atherosclerosis
Neoplasm Invasiveness Antibodies	>32 publications with ST1 and Neoplasm Invasiveness
Coronary Artery Disease Antibodies	>30 publications with ST1 and Coronary Artery Disease
Lung Diseases Antibodies	>30 publications with ST1 and Lung Diseases

Organs/Tissues associated with ST1 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>81 publications with ST1 and Bone
Connective Tissue Antibodies	>44 publications with ST1 and Connective Tissue
Muscle Antibodies	>38 publications with ST1 and Muscle
Lung Antibodies	>35 publications with ST1 and Lung
Brain Antibodies	>35 publications with ST1 and Brain
Skin Antibodies	>30 publications with ST1 and Skin
Eye Antibodies	>15 publications with ST1 and Eye
Uterus Antibodies	>13 publications with ST1 and Uterus
Placenta Antibodies	>12 publications with ST1 and Placenta
Intestine Antibodies	>10 publications with ST1 and Intestine