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LAG-3:fc (LAG) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637219

Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T… More details

$640 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LAG-3:Fc, Active Protein
Full Product Name
LAG-3:Fc, Recombinant, Human (Lymphocyte Activation Gene-3, FDC Protein, CD223)
Sequence
The sequence coding for the 4 extracellu lar Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.
Host
Recombinant human LAG-3 produced in CHO cells.
Form/Format
Supplied as a liquid in PBS
Purity/Purification
Highly Purified
>99% (SDS-PAGE); >99%
Concentration
~0.5 mg/ml; 0.5mg/ml (lot specific)
Specificity
Binds to human, mouse and monkey MHC class II.
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Stable for at least 6 months after receipt when stored at -20 degree C.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the oringinal vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~80kD (SDS-PAGE)
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells.
Endotoxin(LAL)
= or < 0.1EU/ug; < 0.1EU/ug

Product Categories/Family for LAG-3:Fc active protein

Molecular Biology; MB-CD Markers

Other Notes

Small volumes of LAG-3:Fc active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAG-3:Fc purchase

MBS637219 is an active protein targeting LAG-3:Fc. Also known as LAG-3:Fc, Recombinant, Human (Lymphocyte Activation Gene-3, FDC Protein, CD223). Host: Recombinant human LAG-3 produced in CHO cells.
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