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Actin-depolymerizing factor

Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (By similarity).

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Actin-depolymerizing factor 1

Also known as Actin-depolymerizing factor 1 (ADF-1).
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers ().

Actin-depolymerizing factor 1, isoforms a/b

Also known as Actin-depolymerizing factor 1, isoforms a/b (Uncoordinated protein 60).
Depolymerizes growing actin filaments in muscle cells; required for the assembly of actin filaments into the functional contractile myofilament lattice of muscle.

Actin-depolymerizing factor 2

Also known as Actin-depolymerizing factor 2 (ADF-2).
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers ().

Actin-depolymerizing factor 2, isoform c

Also known as Actin-depolymerizing factor 2, isoform c (Uncoordinated protein 60).
Depolymerizes growing actin filaments in muscle cells; required for the assembly of actin filaments into the functional contractile myofilament lattice of muscle.

Actin-depolymerizing factor 7

Also known as Actin-depolymerizing factor 7 (ADF-7) (AtADF7).
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Required for pollen tube growth. Promotes turnover of longitudinal actin cables by severing actin filaments in pollen tubes.

Actin-depolymerizing factor 9

Also known as Actin-depolymerizing factor 9 (ADF-9) (AtADF9).
Does not display typical F-actin depolymerizing activity. Exhibits a high ability to stabilize and cross-link actin filaments. Functions as an actin bundling protein with the highest efficiency under acidic conditions (PubMed:21570971). May play a role in the modulation of levels of histone H3 lysine 4 trimethylation and H3 lysine 9 and 14 acetylation at the FLC locus (PubMed:18830798).

Actin-depolymerizing factor gmf1

Also known as Actin-depolymerizing factor gmf1 (Glia maturation factor-like protein 1).
Actin depolymerizing factor involved in the control of the disassembly of actin patches. Binds and suppresses the arp2/3 complex functions such as the promotion of actin polymerisation and branching filaments.

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