Disco-interacting protein
May provide positional cues for axon pathfinding and patterning in the central nervous system.
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Disco-interacting protein 2
May provide positional cues for axon pathfinding and patterning in the central nervous system.
Disco-interacting protein 2 homolog A
Also known as Disco-interacting protein 2 homolog A (DIP2 homolog A).
DIP2A: May provide positional cues for axon pathfinding and patterning in the central nervous system. Belongs to the DIP2 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Receptor, misc.
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: cell surface
Molecular Function: protein binding
Biological Process: regulation of apoptosis
DIP2A: May provide positional cues for axon pathfinding and patterning in the central nervous system. Belongs to the DIP2 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Receptor, misc.
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: cell surface
Molecular Function: protein binding
Biological Process: regulation of apoptosis
Disco-interacting protein 2 homolog B
Also known as Disco-interacting protein 2 homolog B (DIP2 homolog B).
DIP2B: a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
Protein type: Unknown function
Cellular Component: cytoplasm; membrane; nucleus
DIP2B: a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
Protein type: Unknown function
Cellular Component: cytoplasm; membrane; nucleus
Disco-interacting protein 2 homolog B-A
Also known as Disco-interacting protein 2 homolog B-A (DIP2 homolog B-A).
Disco-interacting protein 2 homolog C
Also known as Disco-interacting protein 2 homolog C (DIP2 homolog C).
DIP2C: a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
Chromosomal Location of Human Ortholog: 10p15.3
DIP2C: a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
Chromosomal Location of Human Ortholog: 10p15.3
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