A Disintegrin and Metalloprotease 19 (ADAM19) ELISA Kit for Human

Name: Human ADAM19 ELISA Kit; A Disintegrin and Metalloprotease 19; MyBioSource
Brand: MyBioSource
SKU: MBS009998
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS009998

MBS009998 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 19 (ADAM19) ELISA Kit target analytes in biological samples. The concentration gradients of… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

A Disintegrin and Metalloprotease 19 (ADAM19), ELISA Kit

Full Product Name

Human A Disintegrin and Metalloprotease 19 ELISA Kit

Product Gene Name

ADAM19 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

104,997 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (156904312..157002783, complement). Location: 5q33.3

OMIM

603640

3D Structure

ModBase 3D Structure for Q9H013

Other Notes

Small volumes of ADAM19 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADAM19. It may not necessarily be applicable to this product.

NCBI GI #

38197238

NCBI GeneID

8728

NCBI Accession #

AAH24214.2

UniProt Primary Accession #

Q9H013

UniProt Secondary Accession #

Q9BZL5; Q9UHP2

UniProt Related Accession #

Q9H013

NCBI Official Full Name

ADAM19 protein, partial

NCBI Official Synonym Full Names

ADAM metallopeptidase domain 19

NCBI Official Symbol

ADAM19

NCBI Official Synonym Symbols

MLTNB; FKSG34; MADDAM

UniProt Protein Name

Disintegrin and metalloproteinase domain-containing protein 19

UniProt Synonym Protein Names

Meltrin-beta; Metalloprotease and disintegrin dendritic antigen marker

Protein Family

Disintegrin and metalloproteinase domain-containing protein

UniProt Gene Name

ADAM19

UniProt Synonym Gene Names

MLTNB; ADAM 19; MADDAM

UniProt Entry Name

ADA19_HUMAN

NCBI Protein Information

disintegrin and metalloproteinase domain-containing protein 19; ADAM 19; meltrin-beta; metalloprotease-disintegrin meltrin beta; metalloprotease and disintegrin dendritic antigen marker; a disintegrin and metalloproteinase domain 19 (meltrin beta)

NCBI Summary for ADAM19

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]

UniProt Comments for ADAM19

ADAM19: Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.-; Membrane protein, integral; Protease; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: integral to membrane

Molecular Function: zinc ion binding; metalloendopeptidase activity; SH3 domain binding

Biological Process: heart development; membrane protein ectodomain proteolysis

Research Articles on ADAM19

1. Prorenin receptor is mainly localized in the subcellular organelles, such as the endoplasmic reticulum and Golgi apparatus, and the prorenin receptor is cleaved by ADAM19 in the Golgi, resulting in two fragments.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ADAM19 elisa kit

Reference Product	PubMed Publications
FURIN elisa kit	>4 publications with ADAM19 and FURIN
NRG1 elisa kit	>3 publications with ADAM19 and NRG1
TNFSF11 elisa kit	>1 publications with ADAM19 and TNFSF11

Diseases associated with ADAM19 elisa kit

Disease Name	Pubmed Publications
Necrosis Antibodies	>14 publications with ADAM19 and Necrosis
Neoplasms Antibodies	>12 publications with ADAM19 and Neoplasms
Cardiovascular Diseases Antibodies	>8 publications with ADAM19 and Cardiovascular Diseases
Nervous System Diseases Antibodies	>5 publications with ADAM19 and Nervous System Diseases
Inflammation Antibodies	>5 publications with ADAM19 and Inflammation
Brain Diseases Antibodies	>4 publications with ADAM19 and Brain Diseases
Heart Defects, Congenital Antibodies	>4 publications with ADAM19 and Heart Defects, Congenital
Kidney Diseases Antibodies	>3 publications with ADAM19 and Kidney Diseases
Ovarian Neoplasms Antibodies	>3 publications with ADAM19 and Ovarian Neoplasms
Atrophy Antibodies	>2 publications with ADAM19 and Atrophy

Organs/Tissues associated with ADAM19 elisa kit

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>15 publications with ADAM19 and Heart
Embryonic Tissue Antibodies	>11 publications with ADAM19 and Embryonic Tissue
Lung Antibodies	>10 publications with ADAM19 and Lung
Brain Antibodies	>9 publications with ADAM19 and Brain
Blood Antibodies	>9 publications with ADAM19 and Blood
Bone Antibodies	>9 publications with ADAM19 and Bone
Kidney Antibodies	>5 publications with ADAM19 and Kidney
Vascular Antibodies	>5 publications with ADAM19 and Vascular
Placenta Antibodies	>4 publications with ADAM19 and Placenta
Lymph Node Antibodies	>3 publications with ADAM19 and Lymph Node