Human LILRB5 Recombinant Protein – Cat# MBS1060053

Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 5 (LILRB5) Human Recombinant Protein

Name: LILRB5 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1060053
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1060053

MBS1060053 is a recombinant protein targeting LILRB5. Also known as Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), Recombinant Protein

Full Product Name

Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5)

Product Gene Name

LILRB5 recombinant protein

Product Synonym Gene Name

LILRB5; LIR8

Product Synonym Names

Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD_antigen=; CD85c

Sequence

GTLPKPT LWAEPASVIA RGKPVTLWCQ GPLETEEYRL DKEGLPWARK RQNPLEPGAK AKFHIPSTVY DSAGRYRCYY ETPAGWSEPS DPLELVATGF YAEPTLLALP SPVVASGGNV TLQCDTLDGL LTFVLVEEEQ KLPRTLYSQK LPKGPSQALF PVGPVTPSCR WRFRCYYYYR KNPQVWSNPS DLLEILVPGV SRKPSLLIPQ GSVVARGGSL TLQCRSDVGY DIFVLYKEGE HDLVQGSGQQ PQAGLSQANF TLGPVSRSHG GQYRCYGAHN LSPRWSAPSD PLDILIAGLI PDIPALSVQP GPKVASGENV TLLCQSWHQI DTFFLTKEGA AHPPLCLKSK YQSYRHQAEF SMSPVTSAQG GTYRCYSAIR SYPYLLSSPS YPQELVVSGP SGDPSLSPTG STPTPGPEDQ PLTPTGLDPQ SGLGRHLG

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

64,197 Da

Sequence Positions

24-458

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

604814

3D Structure

ModBase 3D Structure for O75023

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LILRB5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LILRB5. It may not necessarily be applicable to this product.

NCBI GI #

125987591

NCBI GeneID

10990

NCBI Accession #

NP_001074911.1

UniProt Primary Accession #

O75023

UniProt Secondary Accession #

Q8N760

UniProt Related Accession #

O75023

GenBank Nucleotide #

NM_001081442.1

NCBI Official Full Name

leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 1

NCBI Official Synonym Full Names

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5

NCBI Official Symbol

LILRB5

NCBI Official Synonym Symbols

LIR8; CD85C; LIR-8

UniProt Protein Name

Leukocyte immunoglobulin-like receptor subfamily B member 5

UniProt Synonym Protein Names

CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD_antigen: CD85c

Protein Family

Leukocyte immunoglobulin-like receptor subfamily

UniProt Gene Name

LILRB5

UniProt Synonym Gene Names

LIR8; LIR-8

UniProt Entry Name

LIRB5_HUMAN

NCBI Protein Information

leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; leukocyte immunoglobulin-like receptor 8

NCBI Summary for LILRB5

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for LILRB5

LILRB5: May act as receptor for class I MHC antigens. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane

Molecular Function: transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction; immune system process; defense response

Research Articles on LILRB5

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LILRB5 recombinant protein

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram

Organs/Tissues associated with LILRB5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with LILRB5 and Muscle
Heart Antibodies	>1 publications with LILRB5 and Heart
Blood Antibodies	>1 publications with LILRB5 and Blood