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Odorant Receptor 2a (OR2A) Drosophila Melanogaster Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1093559

MBS1093559 is a recombinant protein targeting Or2a. Also known as Recombinant Drosophila melanogaster Odorant receptor 2a (Or2a). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Odorant receptor 2a (Or2a), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Odorant receptor 2a (Or2a)
Product Gene Name
Product Synonym Gene Name
Or2a; AN4, DOR2F.1, dor62, OR2F.1; CG3206
Product Synonym Names
Recombinant Odorant receptor 2a (Or2a); Odorant receptor 2a
Sequence
MEKQEDFKLN THSAVYYHWR VWELTGLMRP PGVSSLLYVV YSITVNLVVT VLFPLSLLAR LLFTTNMAGL CENLTITITD IVANLKFANV YMVRKQLHEI RSLLRLMDAR ARLVGDPEEI SALRKEVNIA QGTFRTFASI FVFGTTLSCV RVVVRPDREL LYPAWFGVDW MHSTRNYVLI NIYQLFGLIV QAIQNCASDS YPPAFLCLLT GHMRALELRV RRIGCRTEKS NKGQTYEAWR EEVYQELIEC IRDLARVHRL REIIQRVLSV PCMAQFVCSA AVQCTVAMHF LYVADDHDHT AMIISIVFFS AVTLEVFVIC YFGDRMRTQS EALCDAFYDC NWIEQLPKFK RELLFTLART QRPSLIYAGN YIALSLETFE QVMRFTYSVF TLLLRAK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
45,935 Da
Sequence Positions
1-397
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: X; NC_004354.3 (2140264..2141609). Location: 2F2-2F2
3D Structure
ModBase 3D Structure for O46077
Species
Drosophila melanogaster (Fruit fly)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Or2a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Or2a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
odorant receptor 2a
NCBI Official Synonym Full Names
Odorant receptor 2a
NCBI Official Symbol
Or2a
NCBI Official Synonym Symbols
2a; 2F.1; AN4; CG3206; DmelCG3206; DOR2F.1; dor62; Dor62; DOR62; EG:30B8.7; Or2F.1; Or62
UniProt Protein Name
Odorant receptor 2a
Protein Family
UniProt Gene Name
Or2a
UniProt Synonym Gene Names
AN4; DOR2F.1; dor62; OR2F.1
UniProt Entry Name
OR2A_DROME
NCBI Protein Information
CG3206 gene product from transcript CG3206-RA; CG3206-PA; Or2a-PA; odorant receptor 2a; odorant receptor 62; olfactory receptor 2F.1

UniProt Comments for Or2a

Function: Complexes with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. They are necessary and sufficient to promote functional reconstitution of odor-evoked signaling in sensory neurons that normally respond only to carbon dioxide

By similarity.

Subunit structure: Interacts with Orco. Complexes exist early in the endomembrane system in olfactory sensory neurons (OSNs), coupling these complexes to the conserved ciliary trafficking pathway

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Expressed in 20 sensory neurons on the distal edge of the antenna. Ref.5 Ref.6

Miscellaneous: The atypical heteromeric and topological design of the odorant receptors appears to be an insect-specific solution for odor recognition, making the OR/Orco complex an attractive target for the development of highly selective insect repellents to disrupt olfactory-mediated host-seeking behaviors of insect disease vectors. Odor-evoked OR currents are independent of known G-protein-coupled second messenger pathways.

Sequence similarities: Belongs to the heteromeric odorant receptor channel (TC 1.A.69) family. [View classification]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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