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Inward Rectifier Potassium Channel 18 (KCNJ18) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1195694

MBS1195694 is a recombinant protein targeting KCNJ18. Also known as Recombinant Human Inward rectifier potassium channel 18 (KCNJ18), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1895 / 1 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Inward rectifier potassium channel 18 (KCNJ18), Recombinant Protein
Full Product Name
Recombinant Human Inward rectifier potassium channel 18 (KCNJ18), partial
Sequence
AVAHGDLEPA EGHGRTPCVM QVHGFMAAFL FSIETQTTIG YGLRCVTEEC L
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
48,880 Da
Sequence Positions
106-156
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
613236
3D Structure
ModBase 3D Structure for B7U540
Species
Homo sapiens (Human)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KCNJ18 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNJ18. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inward rectifier potassium channel 18
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily J member 18
NCBI Official Symbol
KCNJ18
NCBI Official Synonym Symbols
TTPP2; KIR2.6
UniProt Protein Name
Inward rectifier potassium channel 18
UniProt Synonym Protein Names
Inward rectifier K(+) channel Kir2.6; Potassium channel, inwardly rectifying subfamily J member 18
UniProt Gene Name
KCNJ18
NCBI Protein Information
inward rectifier potassium channel 18

NCBI Summary for KCNJ18

This gene encodes a member of the inwardly rectifying potassium channel family. Transcription of this locus is regulated by thyroid hormone, and the encoded protein plays a role in resting membrane potential maintenance. Mutations in this locus have been associated with thyrotoxic hypokalemic periodic paralysis. [provided by RefSeq, Jan 2013]
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UniProt Comments for KCNJ18

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with KCNJ18 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >6 publications with KCNJ18 and Muscle
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