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IL-3Rbeta Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8501412

MBS8501412 is an antibody targeting IL-3Rbeta. Also known as IL-3Rbeta (Phospho-Tyr593) Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-3Rbeta, Antibody
Full Product Name
IL-3Rbeta (Phospho-Tyr593) Antibody
Product Gene Name
Product Synonym Names
Interleukin-3 receptor alpha chain; IL-3R-alpha; CD123 antigen; IL3RA
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
IL3R (Phospho-Tyr593) antibody detects endogenous levels of IL3R only when phosphorylated at tyrosine 593.
Preparation and Storage
Store at-20 degree C for 1 year
OMIM
308385
3D Structure
ModBase 3D Structure for P26951
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human IL3R around the phosphorylation site of tyrosine 593 (G-P-YP-L-G).
All Sites
Human: Tyr593
Mouse: Tyr595
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IL-3Rbeta antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-IL-3Rbeta antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000

Immunohistochemistry (IHC) of anti-IL-3Rbeta antibody

P-peptide-+ Immunohistochemical analysis of paraffin-embedded human brain tissue using IL3R (Phospho-Tyr593) antibody.
Anti-IL-3Rbeta Antibody – Cat# MBS8501412

Western Blot (WB) of anti-IL-3Rbeta antibody

Western blot analysis of extracts from HepG2 cells, treated with EGF (200ng/ml, 15mins), using IL3R (Phospho-Tyr593) antibody.
Anti-IL-3Rbeta Antibody, Western Blot (WB) – Cat# MBS8501412

Product References and Citations for anti-IL-3Rbeta antibody

Michelle M. Le Beau, Blood, Aug 2003; 102: 1072-1074. Elena Cattaneo, J. Biol. Chem., Sep 1996; 271: 23374. Patricia McLoughlin, J. Biol. Chem., Sep 2002; 277: 37045-37053. Louise Edvardsson, Blood, Nov 2004; 104: 4120.

Other Notes

Small volumes of anti-IL-3Rbeta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-3Rbeta. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-3 receptor subunit alpha isoform 2
NCBI Official Synonym Full Names
interleukin 3 receptor subunit alpha
NCBI Official Symbol
IL3RA
NCBI Official Synonym Symbols
IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra
UniProt Protein Name
Interleukin-3 receptor subunit alpha
UniProt Synonym Protein Names
CD_antigen: CD123
UniProt Gene Name
IL3RA
UniProt Synonym Gene Names
IL3R; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA
NCBI Protein Information
interleukin-3 receptor subunit alpha

NCBI Summary for IL-3Rbeta

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
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UniProt Comments for IL-3Rbeta

This is a receptor for interleukin-3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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