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MGA Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120058

MBS120058 is an antibody targeting MGA. Also known as Mouse monoclonal antibody Anti-Human MGA. Reactive in Human. Host: Mouse. More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MGA, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human MGA
Product Gene Name
anti-MGA antibody
Product Synonym Names
MAX gene associated; KIAA0518; MAD5; MXD5; FLJ12634
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MGA6A4H5
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
336,159 Da
OMIM
616061
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-MGA antibody
Dot Blot (DB)

Quality Control of anti-MGA antibody

Western blot analysis of immunized recombinant protein, using anti-MGA monoclonal antibody.
Mouse Anti-MGA Monoclonal Antibody – Cat# MBS120058

Quality Control #2 of anti-MGA antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-MGA Monoclonal Antibody, Quality Control #2 – Cat# MBS120058

Other Notes

Small volumes of anti-MGA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MGA. It may not necessarily be applicable to this product.

NCBI GI #
34192191
NCBI GeneID
23269
NCBI Accession #
BC038449
UniProt Secondary Accession #
Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9; E7ENI0; F5H7K2
UniProt Related Accession #
Q8IWI9
NCBI Official Full Name
Homo sapiens MAX gene associated, mRNA
NCBI Official Synonym Full Names
MGA, MAX dimerization protein
NCBI Official Symbol
MGA
NCBI Official Synonym Symbols
MAD5; MXD5
UniProt Protein Name
MAX gene-associated protein
UniProt Synonym Protein Names
MAX dimerization protein 5
Protein Family
MAX gene-associated protein
UniProt Gene Name
MGA
UniProt Entry Name
MGAP_HUMAN
NCBI Protein Information
MAX gene-associated protein; MAX dimerization protein 5

UniProt Comments for MGA

MGA iso6: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; DNA-binding

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: nucleoplasm; transcription factor complex; cytoplasm

Molecular Function: protein dimerization activity; DNA binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Research Articles on MGA

1. Results show that inactivation of MGA was observed in both non-small cell lung cancer and SCLC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-MGA antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >20 publications with MGA and Kidney Diseases
 Weight Gain Antibodies  >17 publications with MGA and Weight Gain
 Adenocarcinoma Antibodies  >16 publications with MGA and Adenocarcinoma
 Congenital Abnormalities Antibodies  >15 publications with MGA and Congenital Abnormalities
 Neoplasm Metastasis Antibodies  >9 publications with MGA and Neoplasm Metastasis
 Proteinuria Antibodies  >9 publications with MGA and Proteinuria
 Inflammation Antibodies  >8 publications with MGA and Inflammation
 Necrosis Antibodies  >7 publications with MGA and Necrosis
 Hypertrophy Antibodies  >7 publications with MGA and Hypertrophy
 Hyperplasia Antibodies  >6 publications with MGA and Hyperplasia

Organs/Tissues associated with anti-MGA antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >45 publications with MGA and Muscle
 Brain Antibodies  >38 publications with MGA and Brain
 Nerve Antibodies  >33 publications with MGA and Nerve
 Ovary Antibodies  >31 publications with MGA and Ovary
 Kidney Antibodies  >28 publications with MGA and Kidney
 Liver Antibodies  >27 publications with MGA and Liver
 Skin Antibodies  >20 publications with MGA and Skin
 Lung Antibodies  >15 publications with MGA and Lung
 Uterus Antibodies  >13 publications with MGA and Uterus
 Heart Antibodies  >12 publications with MGA and Heart
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