Human CIB2 Recombinant Protein – Cat# MBS1233458

Calcium and Integrin-Binding Family Member 2 (CIB2) Human Recombinant Protein

Name: CIB2 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1233458
Price: 825 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1233458

The amino acid sequence This protein is similar to that of KIPCIB, calcineurin B, and calmodulin. This suggests that the encoded protein may be a Ca2+-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs). More details

$825 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Calcium and integrin-binding family member 2 (CIB2), Recombinant Protein

Full Product Name

Recombinant Human Calcium and integrin-binding family member 2 (CIB2)

Product Gene Name

CIB2 recombinant protein

Sequence

MGNKQTIFTE EQLDNYQDCT FFNKKDILKL HSRFYELAPN LVPMDYRKSP IVHVPMSLII QMPELRENPF KERIVAAFSE DGEGNLTFND FVDMFSVLCE SAPRELKANY AFKIYDFNTD NFICKEDLEL TLARLTKSEL DEEEVVLVCD KVIEEADLDG DGKLGFADFE DMIAKAPDFL STFHIRI

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

15,816 Da

Sequence Positions

1-187, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

605564

3D Structure

ModBase 3D Structure for O75838

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CIB2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CIB2 purchase

MBS1233458 is a recombinant protein targeting CIB2. Also known as Recombinant Human Calcium and integrin-binding family member 2 (CIB2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CIB2. It may not necessarily be applicable to this product.

NCBI GI #

428980593

NCBI GeneID

10518

NCBI Accession #

NP_001258817.1

UniProt Primary Accession #

O75838

UniProt Secondary Accession #

Q05BT6; B4DDF0; H0YM71

UniProt Related Accession #

O75838

GenBank Nucleotide #

NM_001271888.1

NCBI Official Full Name

calcium and integrin-binding family member 2 isoform 2

NCBI Official Synonym Full Names

calcium and integrin binding family member 2

NCBI Official Symbol

CIB2

NCBI Official Synonym Symbols

KIP2; USH1J; DFNB48

UniProt Protein Name

Calcium and integrin-binding family member 2

UniProt Synonym Protein Names

Kinase-interacting protein 2; KIP 2

Protein Family

Calcium and integrin-binding family

UniProt Gene Name

CIB2

UniProt Synonym Gene Names

KIP2; KIP 2

NCBI Protein Information

calcium and integrin-binding family member 2

NCBI Summary for CIB2

The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

UniProt Comments for CIB2

Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970, PubMed:26426422). May be involved in the mechanotransduction process ().

Research Articles on CIB2

1. results suggest that GJB2 and CIB2 are common cause of hearing loss in different Pakistani ethnicities

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with CIB2 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>4 publications with CIB2 and Nervous System Diseases
Disease Models, Animal Antibodies	>1 publications with CIB2 and Disease Models, Animal

Organs/Tissues associated with CIB2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>2 publications with CIB2 and Muscle
Eye Antibodies	>1 publications with CIB2 and Eye
Testis Antibodies	>1 publications with CIB2 and Testis
Brain Antibodies	>1 publications with CIB2 and Brain