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Disintegrin and Metalloproteinase Domain-Containing Protein 19 (ADAM19) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1244178

MBS1244178 is a recombinant protein targeting Adam19. Also known as Recombinant Mouse Disintegrin and metalloproteinase domain-containing protein 19 (Adam19). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1565 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Disintegrin and metalloproteinase domain-containing protein 19 (Adam19), Recombinant Protein
Full Product Name
Recombinant Mouse Disintegrin and metalloproteinase domain-containing protein 19 (Adam19)
Product Synonym Gene Name
Adam19; Mltnb
Product Synonym Names
Disintegrin and metalloproteinase domain-containing protein 19; ADAM 19; EC=3.4.24.-; Meltrin-beta
Sequence
EDLHSMKYVE LYLVADYAEF QKNRHDQDAT KRKLMEIANY VDKFYRSLNI RIALVGLEVW THGDKCEVSE NPYSTLWSFL SWRRKLLAQK SHDNAQLITG RSFQGTTIGL APLMAMCSVY QSGGVSMDHS ENAIGVASTV AHEIGHNFGM SHDSAHCCSA SAADGGCIMA AATGHPFPKV FSWCNRKELD RYLQTGGGMC LSNMPDTRTL YGGRRCGNGY LEDGEECDCG EEEECKNPCC NASNCTLKEG AECAHGSCCH QCKLVAPGTQ CREQVRQCDL PEFCTGKSPH CPTNYYQMDG TPCEGGQAYC YNGMCLTYQE QCQQLWGPGA RPALDLCFER VNAAGDTYGN CGKGLNGQYR KCSPRDAKCG KIQCQSTQAR PLESNAVSID TTITLNGRRI HCRGTHVYRG PEEEEGEGDM LDPGLVMTGT KCGHNHICFE GQCRNTSFFE TEGCGKKCNG HGVCNNNKNC HCFPGWSPPF CNTPGDGGSV DSGPLPPKSV GPVIAGVFSA LFVLAVLVLL CHCYRQSHKL GKPSALPFKL RHQFSCPFRV SQSGGTGHAN PTFKLQTPQG KRKVTNTPES LRKPSHPPPR PPPDYLRVES PPAPLPAHLN RAAGSSPEAG ARIERKESAR RPPPSRPMPP APNCLLSQDF SRPRPPQKAL PANPVPGQRT GPRSGGTSLL QPPTSGPQPP RPPAVPVPKL PEYRSQRVGA IISSKI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
100,860 Da
Sequence Positions
205-920. Full Length of Mature Protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for O35674
Species
Mus musculus (Mouse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Adam19 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Adam19. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 19 isoform 1 preproprotein
NCBI Official Synonym Full Names
a disintegrin and metallopeptidase domain 19 (meltrin beta)
NCBI Official Symbol
Adam19
NCBI Official Synonym Symbols
Mltnb; AL024287
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 19
UniProt Synonym Protein Names
Meltrin-beta
UniProt Gene Name
Adam19
UniProt Synonym Gene Names
Mltnb; ADAM 19
UniProt Entry Name
ADA19_MOUSE
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 19; meltrin beta; a disintegrin and metalloproteinase domain 19 (meltrin beta)

NCBI Summary for Adam19

This gene encodes a cell surface glycoprotein and member of the ADAM (a disintegrin and metalloproteinase) family of endopeptidases. The encoded protein may play a role in the ectodomain shedding of neuregulin proteins. Homozygous knockout mice for this gene exhibit heart development defects and perinatal lethality. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that undergoes proteolytic processing to generate a mature protein product. [provided by RefSeq, Aug 2015]
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UniProt Comments for Adam19

ADAM19: Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Protease; EC 3.4.24.-

Cellular Component: membrane; integral to membrane

Molecular Function: peptidase activity; protein binding; hydrolase activity; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; metal ion binding; SH3 domain binding

Biological Process: heart development; membrane protein ectodomain proteolysis; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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