Rabbit Anti-L1 Polyclonal Antibody – Cat# MBS1265025

HPV18 Major Capsid Protein L1 (L1) Antibody – Rabbit Polyclonal

Name: L1 Antibody; Polyclonal; Rabbit; Virus-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1265025
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1265025

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HPV18 Major capsid protein L1, Polyclonal Antibody

Full Product Name

Rabbit anti-HPV18 Major capsid protein L1 polyclonal Antibody, HRP conjugated

Product Gene Name

anti-L1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Virus

Purity/Purification

Caprylic Acid Ammonium Sulfate Precipitation Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: L1 (MBS719549)
HRP Conjugated Antibody: L1 (MBS1265025)

Molecular Weight

63,624 Da

3D Structure

ModBase 3D Structure for P06794

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Conjugate

HRP

Immunogen

Recombinant HPV18 Major capsid protein L1 protein

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-L1 antibody

ELISA (EIA)

Other Notes

Small volumes of anti-L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for L1 purchase

MBS1265025 is an antibody targeting L1. Also known as Rabbit anti-HPV18 Major capsid protein L1 polyclonal Antibody, HRP conjugated. Reactive in Virus. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for L1. It may not necessarily be applicable to this product.

NCBI GI #

9626077

NCBI GeneID

1489090

NCBI Accession #

NP_040317.1

UniProt Primary Accession #

P06794

UniProt Secondary Accession #

Q84270

UniProt Related Accession #

CAA28671

GenBank Nucleotide #

NC_001357.1

NCBI Official Full Name

L1 protein

NCBI Official Symbol

UniProt Protein Name

Major capsid protein L1

Protein Family

Major capsid protein

UniProt Gene Name

UniProt Entry Name

VL1_HPV18

NCBI Protein Information

major capsid L1 protein

UniProt Comments for L1

Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.

Research Articles on L1

1. L1 sequences were strongly methylated in all cervical carcinomas studied; hypothesize that L1 is preferentially methylated after integration of the HPV genome into the cellular DNA

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.