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AHSG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127706
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Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions,… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AHSG, Polyclonal Antibody
Full Product Name
AHSG Polyclonal Antibody
Product Gene Name
anti-AHSG antibody
Product Synonym Names
AHS; A2HS; HSGA; FETUA
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
367
OMIM
138680
3D Structure
ModBase 3D Structure for P02765
Species
Human
Immunogen
Recombinant protein of human AHSG
Calculated Molecular Weight
39kDa

Product Categories/Family for anti-AHSG antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AHSG antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-AHSG antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-AHSG antibody

Western blot analysis of extracts of various cell lines, using AHSG antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-AHSG Polyclonal Antibody – Cat# MBS127706

Immunofluorescence (IF) of anti-AHSG antibody

Immunofluorescence analysis of MCF-7 cells using AHSG antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-AHSG Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127706

Other Notes

Small volumes of anti-AHSG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AHSG purchase

MBS127706 is an antibody targeting AHSG. Also known as AHSG Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AHSG. It may not necessarily be applicable to this product.

NCBI GI #
112910
NCBI GeneID
197
NCBI Accession #
P02765.1
UniProt Primary Accession #
P02765
UniProt Secondary Accession #
O14961; O14962; Q9P152; A8K9N6; B2R7G1
UniProt Related Accession #
P02765; AAB29984
NCBI Official Full Name
Alpha-2-HS-glycoprotein
NCBI Official Synonym Full Names
alpha-2-HS-glycoprotein
NCBI Official Symbol
AHSG
NCBI Official Synonym Symbols
AHS; A2HS; HSGA; FETUA
UniProt Protein Name
Alpha-2-HS-glycoprotein
UniProt Synonym Protein Names
Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-ACleaved into the following 2 chains:Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B
Protein Family
Alpha-2-HS-glycoprotein
UniProt Gene Name
AHSG
UniProt Synonym Gene Names
FETUA
UniProt Entry Name
FETUA_HUMAN
NCBI Protein Information
alpha-2-HS-glycoprotein; fetuin-A; alpha-2-Z-globulin; ba-alpha-2-glycoprotein

UniProt Comments for AHSG

FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: extracellular space; extracellular region

Molecular Function: kinase inhibitor activity; cysteine protease inhibitor activity

Biological Process: negative regulation of bone mineralization; pinocytosis; ossification; positive regulation of phagocytosis; regulation of inflammatory response; acute-phase response; negative regulation of insulin receptor signaling pathway; negative regulation of phosphorylation; regulation of bone mineralization; skeletal development
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Research Articles on AHSG

1. Fetuin-A and/or palmitate influence the expression of proinflammatory and angiogenic proteins only partially via TLR4 signalling

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AHSG antibody

 Reference Product  PubMed Publications
 HRG antibody  >4 publications with AHSG and HRG
 ALB antibody  >3 publications with AHSG and ALB
 BMP2 antibody  >2 publications with AHSG and BMP2
 AMBP antibody  >2 publications with AHSG and AMBP
 SERPINC1 antibody  >1 publications with AHSG and SERPINC1
 APOA2 antibody  >1 publications with AHSG and APOA2
 APOH antibody  >1 publications with AHSG and APOH

Pathways associated with anti-AHSG antibody

 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram

Diseases associated with anti-AHSG antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >112 publications with AHSG and Kidney Diseases
 Calcinosis Antibodies  >98 publications with AHSG and Calcinosis
 Inflammation Antibodies  >84 publications with AHSG and Inflammation
 Heart Diseases Antibodies  >55 publications with AHSG and Heart Diseases
 Liver Diseases Antibodies  >45 publications with AHSG and Liver Diseases
 Brain Diseases Antibodies  >21 publications with AHSG and Brain Diseases
 Liver Neoplasms Antibodies  >18 publications with AHSG and Liver Neoplasms
 Fatty Liver Antibodies  >16 publications with AHSG and Fatty Liver
 Myocardial Infarction Antibodies  >15 publications with AHSG and Myocardial Infarction
 Heart Failure Antibodies  >14 publications with AHSG and Heart Failure

Organs/Tissues associated with anti-AHSG antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >497 publications with AHSG and Blood
 Liver Antibodies  >92 publications with AHSG and Liver
 Heart Antibodies  >38 publications with AHSG and Heart
 Muscle Antibodies  >34 publications with AHSG and Muscle
 Brain Antibodies  >19 publications with AHSG and Brain
 Lung Antibodies  >10 publications with AHSG and Lung
 Spleen Antibodies  >4 publications with AHSG and Spleen
 Embryonic Tissue Antibodies  >4 publications with AHSG and Embryonic Tissue
 Thymus Antibodies  >2 publications with AHSG and Thymus
 Testis Antibodies  >2 publications with AHSG and Testis
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