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Atpase Family AAA Domain-Containing Protein 3b (ATAD3B) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1280191

MBS1280191 is a recombinant protein targeting ATAD3B. Also known as Recombinant Human ATPase family AAA domain-containing protein 3B (ATAD3B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1465 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATPase family AAA domain-containing protein 3B (ATAD3B), Recombinant Protein
Full Product Name
Recombinant Human ATPase family AAA domain-containing protein 3B (ATAD3B)
Product Gene Name
ATAD3B recombinant protein
Product Synonym Gene Name
ATAD3B
Sequence
MSWLFGVNKG PKGEGAGPPP PLPPAQPGAE GGGDRGLGDR PAPKDKWSNF DPTGLERAAK AARELEHSRY AKEALNLAQM QEQTLQLEQQ SKLKEYEAAV EQLKSEQIRA QAEERRKTLS EETRQHQARA QYQDKLARQR YEDQLKQQQL LNEENLRKQE ESVQKQEAMR RATVEREMEL RHKNEMLRVE TEARARAKAE RENADIIREQ IRLKASEHRQ TVLESIRTAG TLFGEGFRAF VTDRDKVTAT VAGLTLLAVG VYSAKNATAV TGRFIEARLG KPSLVRETSR ITVLEALRHP IQVSRRLLSR PQDVLEGVVL SPSLEARVRD IAIATRNTKK NRGLYRHILL YGPPGTGKTL FAKKLALHSG MDYAIMTGGD VAPMGREGVT AMHKLFDWAN TSRRGLLLFM DEADAFLRKR ATEEISKDLR ATLNAFLYHM GQHSNKFMLV LASNLPEQFD CAINSRIDVM VHFDLPQQEE RERLVRLHFD NCVLKPATEG KRRLKLAQFD YGRKCSEVAR LTEGMSGREI AQLAVSWQAT AYASKDGVLT EAMMDACVQD AVQQYRQKMR WLKAEGPGRG VEHPLSGVQG ETLTSWSLAT DPSYPCLAGP CTFRICSWMG TGLCPGPLSP RMSCGGGRPF CPPGHPLL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
67,608 Da
Sequence Positions
1-648, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
612317
3D Structure
ModBase 3D Structure for Q5T9A4
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ATAD3B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATAD3B. It may not necessarily be applicable to this product.

NCBI GI #
955080478
NCBI GeneID
83858
NCBI Accession #
NP_001304167.1
UniProt Primary Accession #
Q5T9A4
UniProt Secondary Accession #
Q6ZRB5; Q9BUK4; Q9ULE7; A8K3H1
UniProt Related Accession #
Q5T9A4
GenBank Nucleotide #
NM_001317238.1
NCBI Official Full Name
ATPase family AAA domain-containing protein 3B isoform AAA-TOB3s
NCBI Official Synonym Full Names
ATPase family, AAA domain containing 3B
NCBI Official Symbol
ATAD3B
NCBI Official Synonym Symbols
TOB3; AAA-TOB3
UniProt Protein Name
ATPase family AAA domain-containing protein 3B
UniProt Synonym Protein Names
AAA-TOB3
Protein Family
ATPase family AAA domain-containing protein
UniProt Gene Name
ATAD3B
UniProt Synonym Gene Names
KIAA1273; TOB3
NCBI Protein Information
ATPase family AAA domain-containing protein 3B

NCBI Summary for ATAD3B

The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some cancer cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
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UniProt Comments for ATAD3B

May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes.

Research Articles on ATAD3B

1. ATAD3B region deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ATAD3B recombinant protein

 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram

Diseases associated with ATAD3B recombinant protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with ATAD3B and Breast Neoplasms
 Lung Neoplasms Antibodies  >1 publications with ATAD3B and Lung Neoplasms

Organs/Tissues associated with ATAD3B recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >3 publications with ATAD3B and Embryonic Tissue
 Brain Antibodies  >2 publications with ATAD3B and Brain
 Liver Antibodies  >1 publications with ATAD3B and Liver
 Lung Antibodies  >1 publications with ATAD3B and Lung
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