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RELB Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128227
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MBS128227 is an antibody targeting RELB. Also known as Phospho-RELB-S573 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RELB-S573, Antibody
Full Product Name
Phospho-RELB-S573 Polyclonal Antibody
Product Gene Name
anti-RELB antibody
Product Synonym Names
Phospho-RELB-S573: IREL; I-REL; REL-B
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
579
OMIM
604758
3D Structure
ModBase 3D Structure for Q01201
Species
Human
Route
Synthetic Peptide
Immunogen
A phospho specific peptide corresponding to residues surrounding S573 of human RELB
Calculated Molecular Weight
70kDa

Product Categories/Family for anti-RELB antibody

Phosphorylation
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RELB antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RELB antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100

Western Blot (WB) of anti-RELB antibody

Western blot analysis of extracts from HUVEC cells, using Phospho-RELB-S573 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.
Rabbit Anti-RELB Antibody – Cat# MBS128227

Immunohistochemistry (IHC) of anti-RELB antibody

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-RELB-S573 antibody.
Rabbit Anti-RELB Antibody, Immunohistochemistry (IHC) – Cat# MBS128227

Other Notes

Small volumes of anti-RELB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RELB. It may not necessarily be applicable to this product.

NCBI GI #
92090634
NCBI GeneID
5971
NCBI Accession #
Q01201.2
UniProt Primary Accession #
Q01201
UniProt Secondary Accession #
Q6GTX7; Q9UEI7
UniProt Related Accession #
Q01201
NCBI Official Full Name
Transcription factor RelB
NCBI Official Synonym Full Names
v-rel avian reticuloendotheliosis viral oncogene homolog B
NCBI Official Symbol
RELB
NCBI Official Synonym Symbols
IREL; I-REL; REL-B
UniProt Protein Name
Transcription factor RelB
UniProt Synonym Protein Names
I-Rel
Protein Family
Antitoxin
UniProt Gene Name
RELB
UniProt Entry Name
RELB_HUMAN
NCBI Protein Information
transcription factor RelB; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)

UniProt Comments for RELB

RELB: a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: nucleoplasm; cytoplasm; microtubule organizing center; cytosol

Molecular Function: protein binding; chromatin binding; transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; I-kappaB kinase/NF-kappaB cascade; antigen processing and presentation; response to cytokine stimulus; T-helper 1 cell differentiation; innate immune response; positive regulation of transcription from RNA polymerase II promoter; myeloid dendritic cell differentiation; circadian regulation of gene expression; negative regulation of transcription from RNA polymerase II promoter; inflammatory response
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Research Articles on RELB

1. RelB-p52 dimers were found to directly bind to the IDO promoter, leading to IDO expression in MDSCs

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RELB antibody

 Reference Product  PubMed Publications
 NFKB2 antibody  >99 publications with RELB and NFKB2
 IKBKB antibody  >76 publications with RELB and IKBKB
 CHUK antibody  >32 publications with RELB and CHUK
 NFKB1 antibody  >32 publications with RELB and NFKB1
 BCL3 antibody  >8 publications with RELB and BCL3
 NFKBIA antibody  >7 publications with RELB and NFKBIA
 MAP3K14 antibody  >3 publications with RELB and MAP3K14
 JAK2 antibody  >2 publications with RELB and JAK2
 RAC1 antibody  >1 publications with RELB and RAC1

Pathways associated with anti-RELB antibody

 Products by Pathway  Pathway Diagram
 Alternative NF-kappaB Pathway antibodies  Alternative NF-kappaB Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 IL12-mediated Signaling Events Pathway antibodies  IL12-mediated Signaling Events Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram

Diseases associated with anti-RELB antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >199 publications with RELB and Necrosis
 Inflammation Antibodies  >146 publications with RELB and Inflammation
 Breast Neoplasms Antibodies  >33 publications with RELB and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >21 publications with RELB and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >19 publications with RELB and Cardiovascular Diseases
 Lung Diseases Antibodies  >18 publications with RELB and Lung Diseases
 Kidney Diseases Antibodies  >14 publications with RELB and Kidney Diseases
 Liver Diseases Antibodies  >14 publications with RELB and Liver Diseases
 Neoplasms, Experimental Antibodies  >12 publications with RELB and Neoplasms, Experimental
 Chromosome Aberrations Antibodies  >10 publications with RELB and Chromosome Aberrations

Organs/Tissues associated with anti-RELB antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >288 publications with RELB and Blood
 Bone Marrow Antibodies  >73 publications with RELB and Bone Marrow
 Spleen Antibodies  >51 publications with RELB and Spleen
 Thymus Antibodies  >40 publications with RELB and Thymus
 Lung Antibodies  >37 publications with RELB and Lung
 Vascular Antibodies  >34 publications with RELB and Vascular
 Lymph Node Antibodies  >31 publications with RELB and Lymph Node
 Kidney Antibodies  >31 publications with RELB and Kidney
 Lymph Antibodies  >30 publications with RELB and Lymph
 Muscle Antibodies  >28 publications with RELB and Muscle
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