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DNA-Binding Protein SATB2 (SATB2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1285461

MBS1285461 is a recombinant protein targeting Satb2. Also known as Recombinant Mouse DNA-binding protein SATB2 (Satb2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1595 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA-binding protein SATB2 (Satb2), Recombinant Protein
Full Product Name
Recombinant Mouse DNA-binding protein SATB2 (Satb2)
Product Gene Name
Satb2 recombinant protein
Product Synonym Gene Name
Satb2
Sequence
MERRSESPCL RDSPDRRSGS PDVKGPPPVK VARLEQNGSP MGARGRPNGA VAKAVGGLMI PVFCVVEQLD GSLEYDNREE HAEFVLVRKD VLFSQLVETA LLALGYSHSS AAQAQGIIKL GRWNPLPLSY VTDAPDATVA DMLQDVYHVV TLKIQLQSCS KLEDLPAEQW NHATVRNALK ELLKEMNQST LAKECPLSQS MISSIVNSTY YANVSATKCQ EFGRWYKKYK KIKVERVERE NLSDYCVLGQ RPMHLPNMNQ LASLGKTNEQ SPHSQIHHST PIRNQVPALQ PIMSPGLLSP QLSPQLVRQQ IAMAHLINQQ IAVSRLLAHQ HPQAINQQFL NHPPIPRAVK PEPTNSSVEV SPDIYQQVRD ELKRASVSQA VFARVAFNRT QGLLSEILRK EEDPRTASQS LLVNLRAMQN FLNLPEVERD RIYQDERERS MNPNVSMVSS ASSSPSSSRT PQAKTSTPTT DLPIKVDGAN VNITAAIYDE IQQEMKRAKV SQALFAKVAA NKSQGWLCEL LRWKENPSPE NRTLWENLCT IRRFLNLPQH ERDVIYEEES RHHHSERMQH VVQLPPEPVQ VLHRQQSQPT KESSPPREEA PPPPPPTEDS CAKKPRSRTK ISLEALGILQ SFIHDVGLYP DQEAIHTLSA QLDLPKHTII KFFQNQRYHV KHHGKLKEHL GSAVDVAEYK DEELLTESEE NDSEEGSEEM YKVEAEEENA DKSKAAPAET DQR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
76,039 Da
Sequence Positions
1-733, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8VI24
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Satb2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Satb2. It may not necessarily be applicable to this product.

NCBI GI #
20982839
NCBI GeneID
212712
NCBI Accession #
NP_631885.1
UniProt Primary Accession #
Q8VI24
UniProt Related Accession #
Q8VI24
GenBank Nucleotide #
NM_139146.2
NCBI Official Full Name
DNA-binding protein SATB2
NCBI Official Synonym Full Names
special AT-rich sequence binding protein 2
NCBI Official Symbol
Satb2
NCBI Official Synonym Symbols
mKIAA1034
UniProt Protein Name
DNA-binding protein SATB2
UniProt Synonym Protein Names
Special AT-rich sequence-binding protein 2
Protein Family
DNA-binding protein
UniProt Gene Name
Satb2
UniProt Synonym Gene Names
Kiaa1034
NCBI Protein Information
DNA-binding protein SATB2

UniProt Comments for Satb2

Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating Bcl11b expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
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Research Articles on Satb2

1. Together, these findings demonstrate that Satb2 is critically involved in long-term plasticity processes in the adult forebrain that underlie the consolidation and stabilization of context-linked memory.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Satb2 recombinant protein

 Products by Pathway  Pathway Diagram
 PluriNetWork Pathway antibodies  PluriNetWork Pathway Diagram

Diseases associated with Satb2 recombinant protein

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >20 publications with Satb2 and Congenital Abnormalities
 Craniofacial Abnormalities Antibodies  >15 publications with Satb2 and Craniofacial Abnormalities
 CLEFT PALATE, ISOLATED Antibodies  >14 publications with Satb2 and CLEFT PALATE, ISOLATED
 Cleft Palate Antibodies  >14 publications with Satb2 and Cleft Palate
 Neoplasms Antibodies  >11 publications with Satb2 and Neoplasms
 Nervous System Diseases Antibodies  >7 publications with Satb2 and Nervous System Diseases
 Chromosome Aberrations Antibodies  >7 publications with Satb2 and Chromosome Aberrations
 Nervous System Malformations Antibodies  >3 publications with Satb2 and Nervous System Malformations
 Carcinoma Antibodies  >3 publications with Satb2 and Carcinoma
 Personality Disorders Antibodies  >2 publications with Satb2 and Personality Disorders

Organs/Tissues associated with Satb2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >28 publications with Satb2 and Brain
 Embryonic Tissue Antibodies  >11 publications with Satb2 and Embryonic Tissue
 Spinal Cord Antibodies  >5 publications with Satb2 and Spinal Cord
 Eye Antibodies  >4 publications with Satb2 and Eye
 Bone Marrow Antibodies  >2 publications with Satb2 and Bone Marrow
 Liver Antibodies  >1 publications with Satb2 and Liver
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