Rabbit Anti-BLVRB Polyclonal Antibody – Cat# MBS129205

Western blot analysis of extracts of U-251MG cells, using BLVRB antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

BLVRB Antibody – Rabbit Polyclonal

Name: BLVRB Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129205
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129205

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

BLVRB, Polyclonal Antibody

Full Product Name

BLVRB Polyclonal Antibody

Product Gene Name

anti-BLVRB antibody

Product Synonym Names

FLR; BVRB; SDR43U1; HEL-S-10

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

206

OMIM

600941

3D Structure

ModBase 3D Structure for P30043

Species

Human

Immunogen

Recombinant protein of human BLVRB

Calculated Molecular Weight

22kDa

Product Categories/Family for anti-BLVRB antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-BLVRB antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-BLVRB antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-BLVRB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BLVRB purchase

MBS129205 is an antibody targeting BLVRB. Also known as BLVRB Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BLVRB. It may not necessarily be applicable to this product.

NCBI GI #

1706870

NCBI GeneID

645

NCBI Accession #

P30043.3

UniProt Primary Accession #

P30043

UniProt Secondary Accession #

P32078; P53005; Q32LZ2; A6NKD8; B2R5C6

UniProt Related Accession #

P30043

NCBI Official Full Name

Flavin reductase (NADPH)

NCBI Official Synonym Full Names

biliverdin reductase B

NCBI Official Symbol

BLVRB

NCBI Official Synonym Symbols

FLR; BVRB; SDR43U1; HEL-S-10

UniProt Protein Name

Flavin reductase (NADPH)

UniProt Synonym Protein Names

Biliverdin reductase B (EC:1.3.1.24); BVR-B; Biliverdin-IX beta-reductase; Green heme-binding protein; GHBP; NADPH-dependent diaphorase; NADPH-flavin reductase; FLR

UniProt Gene Name

BLVRB

UniProt Synonym Gene Names

FLR; FR; BVR-B; GHBP; FLR

UniProt Entry Name

BLVRB_HUMAN

NCBI Protein Information

flavin reductase (NADPH); flavin reductase (NADPH); FR; GHBP; BVR-B; NADPH-flavin reductase; NADPH-dependent diaphorase; green heme-binding protein; biliverdin-IX beta-reductase; epididymis secretory protein Li 10; biliverdin reductase B (flavin reductase (NADPH)); short chain dehydrogenase/reductase family 43U, member 1

UniProt Comments for BLVRB

BLVRB: Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.

Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Oxidoreductase; EC 1.5.1.30; EC 1.3.1.24

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol

Molecular Function: flavin reductase activity; biliverdin reductase activity

Biological Process: heme catabolic process; porphyrin metabolic process

Research Articles on BLVRB

1. quantum mechanics/molecular mechanics potential energy surfaces show that the lowest energy pathway proceeds with a positively charged pyrrole intermediate via two transition states

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-BLVRB antibody

Products by Pathway	Pathway Diagram
Heme Degradation Pathway antibodies	Heme Degradation Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Porphyrins Pathway antibodies	Metabolism Of Porphyrins Pathway Diagram
Porphyrin And Chlorophyll Metabolism Pathway antibodies	Porphyrin And Chlorophyll Metabolism Pathway Diagram
Porphyrin And Chlorophyll Metabolism Pathway antibodies	Porphyrin And Chlorophyll Metabolism Pathway Diagram
Riboflavin Metabolism Pathway antibodies	Riboflavin Metabolism Pathway Diagram
Riboflavin Metabolism Pathway antibodies	Riboflavin Metabolism Pathway Diagram
Heme Degradation Pathway antibodies	Heme Degradation Pathway Diagram

Diseases associated with anti-BLVRB antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1 publications with BLVRB and Nervous System Diseases
Liver Diseases Antibodies	>1 publications with BLVRB and Liver Diseases
Carcinoma, Squamous Cell Antibodies	>1 publications with BLVRB and Carcinoma, Squamous Cell
Inflammation Antibodies	>1 publications with BLVRB and Inflammation
Fatty Liver Antibodies	>1 publications with BLVRB and Fatty Liver
Esophageal Squamous Cell Carcinoma Antibodies	>1 publications with BLVRB and Esophageal Squamous Cell Carcinoma

Organs/Tissues associated with anti-BLVRB antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with BLVRB and Blood
Prostate Antibodies	>2 publications with BLVRB and Prostate
Liver Antibodies	>2 publications with BLVRB and Liver
Bone Marrow Antibodies	>1 publications with BLVRB and Bone Marrow
Bone Antibodies	>1 publications with BLVRB and Bone
Ovary Antibodies	>1 publications with BLVRB and Ovary
Lung Antibodies	>1 publications with BLVRB and Lung