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GIP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129812
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This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GIP, Polyclonal Antibody
Full Product Name
GIP Polyclonal Antibody
Product Gene Name
anti-GIP antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
153
OMIM
137240
3D Structure
ModBase 3D Structure for P09681
Species
Human
Immunogen
Recombinant protein of human GIP
Calculated Molecular Weight
17kDa

Product Categories/Family for anti-GIP antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GIP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-GIP antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-GIP antibody

Western blot analysis of extracts of various cell lines, using GIP antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 60s.
Rabbit Anti-GIP Polyclonal Antibody – Cat# MBS129812

Immunohistochemistry (IHC) of anti-GIP antibody

Immunohistochemistry of paraffin-embedded rat kidney using GIP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-GIP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129812

Immunohistochemistry (IHC) of anti-GIP antibody

Immunohistochemistry of paraffin-embedded human colon using GIP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-GIP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129812

Immunohistochemistry (IHC) of anti-GIP antibody

Immunohistochemistry of paraffin-embedded human colon carcinoma using GIP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-GIP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129812

Immunohistochemistry (IHC) of anti-GIP antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using GIP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-GIP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129812

Other Notes

Small volumes of anti-GIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GIP purchase

MBS129812 is an antibody targeting GIP. Also known as GIP Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GIP. It may not necessarily be applicable to this product.

NCBI GI #
121194
NCBI GeneID
2695
NCBI Accession #
P09681.1
UniProt Primary Accession #
P09681
UniProt Secondary Accession #
Q4VB42; Q6NTD3
UniProt Related Accession #
P09681
NCBI Official Full Name
Gastric inhibitory polypeptide
NCBI Official Synonym Full Names
gastric inhibitory polypeptide
NCBI Official Symbol
GIP
UniProt Protein Name
Gastric inhibitory polypeptide
UniProt Synonym Protein Names
Glucose-dependent insulinotropic polypeptide; Incretin hormone
Protein Family
Copia protein
UniProt Gene Name
GIP
UniProt Synonym Gene Names
GIP
UniProt Entry Name
GIP_HUMAN
NCBI Protein Information
gastric inhibitory polypeptide; incretin hormone; glucose-dependent insulinotropic polypeptide

UniProt Comments for GIP

GIP: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Belongs to the glucagon family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.3-q22

Cellular Component: extracellular space; cell soma; endoplasmic reticulum lumen; extracellular region

Molecular Function: hormone activity

Biological Process: response to drug; response to peptide hormone stimulus; adult locomotory behavior; positive regulation of insulin secretion; female pregnancy; sensory perception of pain; response to amino acid stimulus; signal transduction; response to lipid; endocrine pancreas development; response to organic cyclic substance; memory; response to starvation; response to selenium ion; cellular protein metabolic process; response to glucose stimulus; response to axon injury; regulation of insulin secretion
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Research Articles on GIP

1. Data from studies in healthy Japanese men suggest that plasma GIP levels in postprandial period are dose dependently increased by fat content of meals of ordinary size, despite the amount of additional fat being relatively small.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GIP antibody

 Reference Product  PubMed Publications
 GIPR antibody  >99 publications with GIP and GIPR
 DPP4 antibody  >53 publications with GIP and DPP4
 BAX antibody  >5 publications with GIP and BAX
 GATA4 antibody  >3 publications with GIP and GATA4
 RETN antibody  >2 publications with GIP and RETN
 ISL1 antibody  >1 publications with GIP and ISL1

Pathways associated with anti-GIP antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Incretin Synthesis, Secretion, And Inactivation Pathway antibodies  Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram

Diseases associated with anti-GIP antibody

 Disease Name  Pubmed Publications
 Diabetes Mellitus, Type 2 Antibodies  >458 publications with GIP and Diabetes Mellitus, Type 2
 Weight Loss Antibodies  >103 publications with GIP and Weight Loss
 Cardiovascular Diseases Antibodies  >89 publications with GIP and Cardiovascular Diseases
 Weight Gain Antibodies  >63 publications with GIP and Weight Gain
 Carcinoma Antibodies  >47 publications with GIP and Carcinoma
 Hyperplasia Antibodies  >41 publications with GIP and Hyperplasia
 Kidney Diseases Antibodies  >33 publications with GIP and Kidney Diseases
 Hypertension Antibodies  >26 publications with GIP and Hypertension
 Fatty Liver Antibodies  >25 publications with GIP and Fatty Liver
 Necrosis Antibodies  >24 publications with GIP and Necrosis

Organs/Tissues associated with anti-GIP antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >484 publications with GIP and Intestine
 Stomach Antibodies  >156 publications with GIP and Stomach
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