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TIA1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2554601

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TIA1, Polyclonal Antibody
Full Product Name
TIA1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
Cytotoxic granule associated RNA binding protein 1; Cytotoxic granule associated RNA binding protein; mTIA-1; Nucleolysin TIA 1 isoform p40; Nucleolysin TIA-1 isoform p40; Nucleolysin TIA1 isoform p40; p40 TIA 1; p40-TIA-1 (containing p15-TIA-1); p40-TIA-1; RNA binding protein TIA 1; RNA binding protein TIA1; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA 1; TIA 1 cytotoxic granule associated RNA binding protein; Tia; TIA-1; TIA1; TIA1 cytotoxic granule associated RNA binding protein; TIA1 cytotoxic granule associated RNA binding protein like 1; TIA1 protein; TIA1; TIAL1; TIAR; WDM
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Affinity Purification
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
Calculated: 24kDa; 41kDa; 42kDa
Observed: 43kDa; 53kDa
3D Structure
ModBase 3D Structure for P31483
Immunogen
A synthetic peptide of human TIA1
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TIA1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TIA1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-TIA1 antibody

Western blot analysis of extracts of various cell lines, using TIA1 antibody.
Rabbit Anti-TIA1 Polyclonal Antibody – Cat# MBS2554601

Immunohistochemistry (IHC) of anti-TIA1 antibody

Immunohistochemistry of paraffin-embedded human colon carcinoma using TIA1 antibody.
Rabbit Anti-TIA1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2554601

Immunohistochemistry (IHC) of anti-TIA1 antibody

Immunohistochemistry of paraffin-embedded human stomach using TIA1 antibody.
Rabbit Anti-TIA1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2554601

Other Notes

Small volumes of anti-TIA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TIA1 purchase

MBS2554601 is an antibody targeting TIA1. Also known as TIA1 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TIA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nucleolysin TIA-1 isoform p40 isoform 1
NCBI Official Synonym Full Names
TIA1 cytotoxic granule associated RNA binding protein
NCBI Official Symbol
TIA1
NCBI Official Synonym Symbols
WDM; TIA-1
UniProt Protein Name
Nucleolysin TIA-1 isoform p40
UniProt Synonym Protein Names
RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA-1; p40-TIA-1
Protein Family
UniProt Gene Name
TIA1
UniProt Synonym Gene Names
TIA-1
NCBI Protein Information
nucleolysin TIA-1 isoform p40; nucleolysin TIA-1

NCBI Summary for TIA1

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]
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UniProt Comments for TIA1

Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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