Trypanosoma Brucei Brucei JBP2 Recombinant Protein – Cat# MBS1308535

Bifunctional Helicase and Thymine Dioxygenase JBP2 (JBP2), Partial (JBP2) Trypanosoma Brucei Brucei Recombinant Protein

Name: JBP2 Recombinant Protein; Trypanosoma Brucei Brucei; MyBioSource
Brand: MyBioSource
SKU: MBS1308535
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1308535

MBS1308535 is a recombinant protein targeting JBP2. Also known as Recombinant Trypanosoma brucei brucei Bifunctional helicase and thymine dioxygenase JBP2 (JBP2), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Bifunctional helicase and thymine dioxygenase JBP2 (JBP2), partial, Recombinant Protein

Full Product Name

Recombinant Trypanosoma brucei brucei Bifunctional helicase and thymine dioxygenase JBP2 (JBP2), partial

Product Gene Name

JBP2 recombinant protein

Product Synonym Gene Name

JBP2; Tb927.7.4650

Product Synonym Names

Bifunctional helicase and thymine dioxygenase JBP2; J-binding protein 2; TbJBP2; Including the following 2 domains:; Probable DNA helicase JBP2; EC=3.6.4.12; Thymine dioxygenase JBP2; EC=1.14.11.6

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

121,447 Da

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q57X81

Species

Trypanosoma brucei brucei (strain 927/4 GUTat10.1)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of JBP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for JBP2. It may not necessarily be applicable to this product.

NCBI GI #

72391588

NCBI GeneID

3658676

NCBI Accession #

XP_846088.1

UniProt Primary Accession #

Q57X81

UniProt Related Accession #

Q57X81

GenBank Nucleotide #

XM_840995.1

NCBI Official Full Name

SNF2 DNA repair protein

NCBI Official Symbol

Tb927.7.4650

NCBI Official Synonym Symbols

Tb07.26A24.600

UniProt Protein Name

Bifunctional helicase and thymine dioxygenase JBP2

UniProt Synonym Protein Names

J-binding protein 2; TbJBP2

Protein Family

Bifunctional helicase and thymine dioxygenase

UniProt Gene Name

JBP2

UniProt Synonym Gene Names

TbJBP2

UniProt Entry Name

JBP2_TRYB2

NCBI Protein Information

SNF2 DNA repair protein

UniProt Comments for JBP2

Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Probably also acts as a DNA helicase. Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis. Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis. In contrast to JBP1, it does not specifically bind DNA base J, it however binds chromatin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.