Mouse ACSS2 Recombinant Protein – Cat# MBS1314085

Acetyl-Coenzyme A Synthetase, Cytoplasmic (ACSS2) Mouse Recombinant Protein

Name: ACSS2 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1314085
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1314085

Activates acetate so that it can be used for lipid synthesis or for energy generation. More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Acetyl-coenzyme A synthetase, cytoplasmic (Acss2), Recombinant Protein

Full Product Name

Recombinant Mouse Acetyl-coenzyme A synthetase, cytoplasmic (Acss2)

Product Gene Name

Acss2 recombinant protein

Product Synonym Gene Name

Acss2; Acas2; Acecs1

Product Synonym Names

Acetyl-coenzyme A synthetase, cytoplasmic; EC=6.2.1.1; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme

Sequence

MGLPEERRKS GSGSRAREET GAEGRVRGWS PPPEVRRSAH VPSLQRYREL HRRSVEEPRE FWGNIAKEFY WKTACPGPFL QYNFDVTKGK IFTEWMKGAT TNICYNVLDR NVHEKKLGDK VAFYWEGNEP GETTKITYRE LLVQVCQFSN VLRKQGIQKG DRVAIYMPMI LELVVAMLAC ARLGALHSIV FAGFSAESLC ERILDSSCCL LITTDAFYRG EKLVNLKELA DESLEKCREK GFPVRCCIVV KHLGRAELGM NDSPSQSPPV KRPCPDVQIC WNEGVDLWWH ELMQQAGDEC EPEWCDAEDP LFILYTSGST GKPKGVVHTI GGYMLYVATT FKYVFDFHPE DVFWCTADIG WITGHSYVTY GPLANGATSV LFEGIPTYPD EGRLWSIVDK YKVTKFYTAP TAIRMLMKFG DDPVTKHSRA SLQVLGTVGE PINPEAWLWY HRVVGSQRCP IVDTFWQTET GGHMLTPLPG ATPMKPGSAS FPFFGVAPAI LNESGEELEG EAEGYLVFKQ PWPGIMRTVY GNHTRFETTY FKKFPGYYVT GDGCRRDQDG YYWITGRIDD MLNVSGHLLS TAEVESALVE HEAVAEAAVV GHPHPVKGEC LYCFVTLCDG HTFSPTLTEE LKKQIREKIG PIATPDYIQN APGLPKTRSG KIMRRVLRKI AQNDHDLGDT STVADPSVIN HLFSHRCLTT Q

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

82.9 kDa

Sequence Positions

1-701. Full Length Protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q9QXG4

Species

Mus musculus (Mouse)

Production Note

Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

Product Categories/Family for Acss2 recombinant protein

Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Acss2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Acss2 purchase

MBS1314085 is a recombinant protein targeting Acss2. Also known as Recombinant Mouse Acetyl-coenzyme A synthetase, cytoplasmic (Acss2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Acss2. It may not necessarily be applicable to this product.

NCBI GI #

31980996

NCBI GeneID

60525

NCBI Accession #

NP_062785.2

UniProt Primary Accession #

Q9QXG4

UniProt Secondary Accession #

Q8BK97

UniProt Related Accession #

Q9QXG4

GenBank Nucleotide #

NM_019811.3

NCBI Official Full Name

acetyl-coenzyme A synthetase, cytoplasmic

NCBI Official Synonym Full Names

acyl-CoA synthetase short-chain family member 2

NCBI Official Symbol

Acss2

NCBI Official Synonym Symbols

ACAS; Acs1; Acas1; Acas2; AceCS1; 1110017C11Rik

UniProt Protein Name

Acetyl-coenzyme A synthetase, cytoplasmic

UniProt Synonym Protein Names

Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme

Protein Family

Acetyl-coenzyme A synthetase

UniProt Gene Name

Acss2

UniProt Synonym Gene Names

Acas2; Acecs1; ACS; AceCS

UniProt Entry Name

ACSA_MOUSE

NCBI Protein Information

acetyl-coenzyme A synthetase, cytoplasmic; ACS; aceCS; acetate--CoA ligase; acyl-activating enzyme; acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 1 (AMP forming); acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-Coenzyme A synthetase 2 (AMP forming)

UniProt Comments for Acss2

ACSS2: Activates acetate so that it can be used for lipid synthesis or for energy generation. Monomer. Belongs to the ATP-dependent AMP-binding enzyme family.

Protein type: Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Ligase; Carbohydrate Metabolism - propanoate; EC 6.2.1.1

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm

Molecular Function: acetate-CoA ligase activity; nucleotide binding; catalytic activity; ATP binding; ligase activity

Biological Process: metabolic process; lipid biosynthetic process; acetyl-CoA biosynthetic process; propionate biosynthetic process; acetate biosynthetic process

Research Articles on Acss2

1. Acss2 generates a specific pool of acetyl CoA during hypoxia that modulates interactions of the acetylase/coactivator Cbp (also known as Crebbp) with the stress-responsive transcription factor, Hif-2. Because erythropoietin is a Hif-2 target gene, red blood cell production in mice is also regulated by Acss2. Recovery from anemia is accelerated by administering acetate, although this requires the presence of Acss2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Acss2 recombinant protein

Products by Pathway	Pathway Diagram
Amino Acid Conjugation Of Benzoic Acid Pathway antibodies	Amino Acid Conjugation Of Benzoic Acid Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Ethanol Oxidation Pathway antibodies	Ethanol Oxidation Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram
Fatty Acid Biosynthesis Pathway antibodies	Fatty Acid Biosynthesis Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with Acss2 recombinant protein

Disease Name	Pubmed Publications
Insulin Resistance Antibodies	>3 publications with Acss2 and Insulin Resistance
Atherosclerosis Antibodies	>2 publications with Acss2 and Atherosclerosis
Hyperglycemia Antibodies	>2 publications with Acss2 and Hyperglycemia
Fatty Liver Antibodies	>2 publications with Acss2 and Fatty Liver
Weight Gain Antibodies	>2 publications with Acss2 and Weight Gain
Glucose Intolerance Antibodies	>2 publications with Acss2 and Glucose Intolerance
Breast Neoplasms Antibodies	>1 publications with Acss2 and Breast Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with Acss2 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with Acss2 and Liver Neoplasms
Liver Diseases Antibodies	>1 publications with Acss2 and Liver Diseases

Organs/Tissues associated with Acss2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>5 publications with Acss2 and Liver
Adipose Tissue Antibodies	>3 publications with Acss2 and Adipose Tissue
Heart Antibodies	>2 publications with Acss2 and Heart
Extraembryonic Tissue Antibodies	>1 publications with Acss2 and Extraembryonic Tissue
Embryonic Tissue Antibodies	>1 publications with Acss2 and Embryonic Tissue
Kidney Antibodies	>1 publications with Acss2 and Kidney
Mammary Gland Antibodies	>1 publications with Acss2 and Mammary Gland