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Protein IWS1 Homolog (IWS1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1319065

MBS1319065 is a recombinant protein targeting Iws1. Also known as Recombinant Mouse Protein IWS1 homolog (Iws1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1635 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein IWS1 homolog (Iws1), Recombinant Protein
Full Product Name
Recombinant Mouse Protein IWS1 homolog (Iws1)
Product Gene Name
Iws1 recombinant protein
Product Synonym Gene Name
Iws1
Sequence
MDSEYYSGDQ SDDGGATPVQ DERDSGSDGE DGVTEQHSGS DTGSVDHHSE NETSDREDGL AKIHNGTDSE NDEPSNANAS DSESEELHRP KDSDSDSEEH AESPASDSEN EPVNQHGSDS ENEELLNGHA SDSEKEEVSK HAASDSEAED TLQPQVSESD SEDPPRPQAS DSENEEPPKP RISDSESEEL PKPRVSDSES EDPPRPQASD SESEELPKPR VSDSESEDPP RPQASDSESE ELPKPRVSDS ESEDPQKGPA SDSEAEDASR HKEKPDSDDS DGENKREDSE VQNESDGHTD RKGLHSSDSE EEEPKRQKID SDDDEEKEGD EEKVAKRKAA VLSDSEDDAG NASAKKSRVV CDADDSDSDV VSDKSGKRET TVASDSEEEA GKEESSVKKK EDKDLFGSDS ESGNEEENLI ADIFGESGDE EEEEFTGFNQ EDLEEEKNET QLKEAEDSDS DDNIKRGKHM DFLSDFEMML QRKKSMCGKR RRNRDGGTFI SDADDVVSAM IVKMNEAAEE DRQLNNQKKP ALKKLTLLPT VVMHLKKQDL KETFIDSGVM SAIKEWLSPL PDRSLPALKI REELLKILQE LPSVSQETLK HSGIGRAVMY LYKHPKESRS NKDMAGKLIN EWSRPIFGLT SNYKGMTREE REQRDLEQMP QRRRLSSTGG QTPRRDLEKV LTGEEKALRP GDPGFCARAR VPMPSNKDYV VRPKWNVEME SSRFQASSKK GISRLDKQMR KFTDIRKKSR SAHAVKISIE GNKMPL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
59,298 Da
Sequence Positions
1-766, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8C1D8
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Iws1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Iws1. It may not necessarily be applicable to this product.

NCBI GI #
30352010
NCBI GeneID
73473
NCBI Accession #
NP_775617.1
UniProt Primary Accession #
Q8C1D8
UniProt Secondary Accession #
Q3TQ25; Q3UWB0; Q6NVD1; Q8BY73; Q9D9H4
UniProt Related Accession #
Q8C1D8
GenBank Nucleotide #
NM_173441.3
NCBI Official Full Name
protein IWS1 homolog
NCBI Official Synonym Full Names
IWS1, SUPT6 interacting protein
NCBI Official Symbol
Iws1
NCBI Official Synonym Symbols
AL117927; AW214353; 3000008H23; 1700069O15Rik
UniProt Protein Name
Protein IWS1 homolog
UniProt Synonym Protein Names
IWS1-like protein
Protein Family
Protein
UniProt Gene Name
Iws1
UniProt Synonym Gene Names
Iws1l
NCBI Protein Information
protein IWS1 homolog

UniProt Comments for Iws1

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Iws1 recombinant protein

 Products by Pathway  Pathway Diagram
 Fatty Acid Beta-oxidation I Pathway antibodies  Fatty Acid Beta-oxidation I Pathway Diagram

Diseases associated with Iws1 recombinant protein

 Disease Name  Pubmed Publications
 Gastrointestinal Diseases Antibodies  >1 publications with Iws1 and Gastrointestinal Diseases

Organs/Tissues associated with Iws1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with Iws1 and Lung
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