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Ap-4 Complex Subunit Epsilon-1 (AP4E1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1325982

MBS1325982 is a recombinant protein targeting Ap4e1. Also known as Recombinant Mouse AP-4 complex subunit epsilon-1 (Ap4e1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AP-4 complex subunit epsilon-1 (Ap4e1), Recombinant Protein
Full Product Name
Recombinant Mouse AP-4 complex subunit epsilon-1 (Ap4e1) , partial
Product Gene Name
Ap4e1 recombinant protein
Product Synonym Gene Name
Ap4e1
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
124,845 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q80V94
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ap4e1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ap4e1. It may not necessarily be applicable to this product.

NCBI GI #
124487335
NCBI GeneID
108011
NCBI Accession #
NP_780759.2
UniProt Primary Accession #
Q80V94
UniProt Secondary Accession #
A2ASB4
UniProt Related Accession #
Q80V94
GenBank Nucleotide #
NM_175550.3
NCBI Official Full Name
AP-4 complex subunit epsilon-1
NCBI Official Synonym Full Names
adaptor-related protein complex AP-4, epsilon 1
NCBI Official Symbol
Ap4e1
NCBI Official Synonym Symbols
AV087807; 2310033A20Rik; 9930028M04Rik
UniProt Protein Name
AP-4 complex subunit epsilon-1
UniProt Synonym Protein Names
AP-4 adaptor complex subunit epsilon; Adaptor-related protein complex 4 subunit epsilon-1; Epsilon subunit of AP-4; Epsilon-adaptin
Protein Family
AP-4 complex
UniProt Gene Name
Ap4e1
NCBI Protein Information
AP-4 complex subunit epsilon-1

UniProt Comments for Ap4e1

Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Ap4e1 recombinant protein

 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram

Diseases associated with Ap4e1 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with Ap4e1 and Nervous System Diseases
 Central Nervous System Diseases Antibodies  >1 publications with Ap4e1 and Central Nervous System Diseases
 Musculoskeletal Abnormalities Antibodies  >1 publications with Ap4e1 and Musculoskeletal Abnormalities
 Craniofacial Abnormalities Antibodies  >1 publications with Ap4e1 and Craniofacial Abnormalities
 Congenital Abnormalities Antibodies  >1 publications with Ap4e1 and Congenital Abnormalities

Organs/Tissues associated with Ap4e1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with Ap4e1 and Brain
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