Human KIAA0196 Recombinant Protein – Cat# MBS1339609

WASH Complex Subunit Strumpellin (KIAA0196) Human Recombinant Protein

Name: KIAA0196 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1339609
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1339609

This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WASH complex subunit strumpellin (KIAA0196), Recombinant Protein

Full Product Name

Recombinant Human WASH complex subunit strumpellin (KIAA0196) , partial

Product Gene Name

KIAA0196 recombinant protein

Product Synonym Gene Name

KIAA0196

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

134,286 Da

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

220210

3D Structure

ModBase 3D Structure for Q12768

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KIAA0196 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIAA0196 purchase

MBS1339609 is a recombinant protein targeting KIAA0196. Also known as Recombinant Human WASH complex subunit strumpellin (KIAA0196) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for KIAA0196. It may not necessarily be applicable to this product.

NCBI GI #

120952851

NCBI GeneID

9897

NCBI Accession #

NP_055661.3

UniProt Primary Accession #

Q12768

UniProt Secondary Accession #

Q3KQX5; Q8TBQ2; A8K4R7

UniProt Related Accession #

Q12768

GenBank Nucleotide #

NM_014846.3

NCBI Official Full Name

WASH complex subunit 5 isoform 1

NCBI Official Synonym Full Names

WASH complex subunit 5

NCBI Official Symbol

WASHC5

NCBI Official Synonym Symbols

RTSC; SPG8; RTSC1; KIAA0196

UniProt Protein Name

WASH complex subunit 5

UniProt Synonym Protein Names

Strumpellin; WASH complex subunit strumpellinCurated

Protein Family

WASH complex

UniProt Gene Name

WASHC5

NCBI Protein Information

WASH complex subunit 5; WASH complex subunit strumpellin

UniProt Comments for KIAA0196

Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). May be involved in axonal outgrowth. Involved in cellular localization of ADRB2 (PubMed:23085491). Involved in cellular trafficking of BLOC-1 complex cargos such as ATP7A and VAMP7 (PubMed:23676666).

Research Articles on KIAA0196

1. A novel missense mutation was identified in the KIAA0196 gene in a Japanese patient with SPG8.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KIAA0196 recombinant protein

Reference Product	PubMed Publications
WASH1 recombinant protein	>2 publications with KIAA0196 and WASH1
KIAA1033 recombinant protein	>2 publications with KIAA0196 and KIAA1033
CCDC53 recombinant protein	>1 publications with KIAA0196 and CCDC53

Diseases associated with KIAA0196 recombinant protein

Disease Name	Pubmed Publications
Neurodegenerative Diseases Antibodies	>6 publications with KIAA0196 and Neurodegenerative Diseases
Neoplasm Metastasis Antibodies	>2 publications with KIAA0196 and Neoplasm Metastasis
Heart Diseases Antibodies	>1 publications with KIAA0196 and Heart Diseases
Neoplasm Invasiveness Antibodies	>1 publications with KIAA0196 and Neoplasm Invasiveness
Colonic Neoplasms Antibodies	>1 publications with KIAA0196 and Colonic Neoplasms

Organs/Tissues associated with KIAA0196 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>6 publications with KIAA0196 and Brain
Prostate Antibodies	>3 publications with KIAA0196 and Prostate
Muscle Antibodies	>2 publications with KIAA0196 and Muscle
Bladder Antibodies	>2 publications with KIAA0196 and Bladder
Heart Antibodies	>2 publications with KIAA0196 and Heart
Nerve Antibodies	>1 publications with KIAA0196 and Nerve
Skin Antibodies	>1 publications with KIAA0196 and Skin
Bone Antibodies	>1 publications with KIAA0196 and Bone