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UPF0532 Protein C7orf60 (C7ORF60) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1345506

MBS1345506 is a recombinant protein targeting C7orf60. Also known as Recombinant Human UPF0532 protein C7orf60 (C7orf60). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1145 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UPF0532 protein C7orf60 (C7orf60), Recombinant Protein
Full Product Name
Recombinant Human UPF0532 protein C7orf60 (C7orf60)
Product Gene Name
C7orf60 recombinant protein
Product Synonym Gene Name
C7orf60
Sequence
MEPGAGGRNT ARAQRAGSPN TPPPREQERK LEQEKLSGVV KSVHRRLRKK YREVGDFDKI WREHCEDEET LCEYAVAMKN LADNHWAKTC EGEGRIEWCC SVCREYFQNG GKRKALEKDE KRAVLATKTT PALNMHESSQ LEGHLTNLSF TNPEFITELL QASGKIRLLD VGSCFNPFLK FEEFLTVGID IVPAVESVYK CDFLNLQLQQ PLQLAQDAID AFLKQLKNPI DSLPGELFHV VVFSLLLSYF PSPYQRWICC KKAHELLVLN GLLLIITPDS SHQNRHAMMM KSWKIAIESL GFKRFKYSKF SHMHLMAFRK ISLKTTSDLV SRNYPGMLYI PQDFNSIEDE EYSNPSCYVR SDIEDEQLAY GFTELPDAPY DSDSGESQAS SIPFYELEDP ILLLS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
46,324 Da
Sequence Positions
1-405, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q1RMZ1
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of C7orf60 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C7orf60. It may not necessarily be applicable to this product.

NCBI GI #
116812632
NCBI GeneID
154743
NCBI Accession #
NP_689769.2
UniProt Primary Accession #
Q1RMZ1
UniProt Secondary Accession #
Q8N3D0; Q96MV7
UniProt Related Accession #
Q1RMZ1
GenBank Nucleotide #
NM_152556.2
NCBI Official Full Name
S-adenosylmethionine sensor upstream of mTORC1
NCBI Official Synonym Full Names
base methyltransferase of 25S rRNA 2 homolog
NCBI Official Symbol
BMT2
NCBI Official Synonym Symbols
SAMTOR; C7orf60
UniProt Protein Name
S-adenosylmethionine sensor upstream of mTORC1
UniProt Synonym Protein Names
Probable methyltransferase BMT2 homolog
UniProt Gene Name
BMT2
NCBI Protein Information
S-adenosylmethionine sensor upstream of mTORC1

UniProt Comments for C7orf60

S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes (PubMed:29123071). Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling (PubMed:29123071). Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling (PubMed:29123071). Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase (Potential).
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Research Articles on C7orf60

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with C7orf60 recombinant protein

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with C7orf60 and Disease Models, Animal
 Inflammation Antibodies  >2 publications with C7orf60 and Inflammation
 Precancerous Conditions Antibodies  >1 publications with C7orf60 and Precancerous Conditions
 Weight Loss Antibodies  >1 publications with C7orf60 and Weight Loss

Organs/Tissues associated with C7orf60 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >7 publications with C7orf60 and Bone
 Bone Marrow Antibodies  >7 publications with C7orf60 and Bone Marrow
 Blood Antibodies  >2 publications with C7orf60 and Blood
 Intestine Antibodies  >1 publications with C7orf60 and Intestine
 Stomach Antibodies  >1 publications with C7orf60 and Stomach
 Mouth Antibodies  >1 publications with C7orf60 and Mouth
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