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Homeodomain-Interacting Protein Kinase 4 (HIPK4) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1353412

MBS1353412 is a recombinant protein targeting HIPK4. Also known as Recombinant Human Homeodomain-interacting protein kinase 4 (HIPK4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1425 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Homeodomain-interacting protein kinase 4 (HIPK4), Recombinant Protein
Full Product Name
Recombinant Human Homeodomain-interacting protein kinase 4 (HIPK4)
Product Gene Name
Product Synonym Gene Name
HIPK4
Sequence
MSTIQSETDC YDIIEVLGKG TFGEVAKGWR RSTGEMVAIK ILKNDAYRNR IIKNELKLLH CMRGLDPEEA HVIRFLEFFH DALKFYLVFE LLEQNLFEFQ KENNFAPLPA RHIRTVTLQV LTALARLKEL AIIHADLKPE NIMLVDQTRC PFRVKVIDFG SASIFSEVRY VKEPYIQSRF YRAPEILLGL PFCEKVDVWS LGCVMAELHL GWPLYPGNNE YDQVRYICET QGLPKPHLLH AACKAHHFFK RNPHPDAANP WQLKSSADYL AETKVRPLER RKYMLKSLDQ IETVNGGSVA SRLTFPDREA LAEHADLKSM VELIKRMLTW ESHERISPSA ALRHPFVSMQ QLRSAHETTH YYQLSLRSYR LSLQVEGKPP TPVVAAEDGT PYYCLAEEKE AAGMGSVAGS SPFFREEKAP GMQRAIDQLD DLSLQEAGHG LWGETCTNAV SDMMVPLKAA ITGHHVPDSG PEPILAFYSS RLAGRHKARK PPAGSKSDSN FSNLIRLSQV SPEDDRPCRG SSWEEGEHLG ASAEPLAILQ RDEDGPNIDN MTMEAERPDP ELFDPSSCPG EWLSEPDCTL ESVRGPRAQG LPPRRSHQHG PPRGATSFLQ HVTGHH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
69,425 Da
Sequence Positions
1-616, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
611712
3D Structure
ModBase 3D Structure for Q8NE63
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HIPK4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HIPK4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeodomain-interacting protein kinase 4
NCBI Official Synonym Full Names
homeodomain interacting protein kinase 4
NCBI Official Symbol
HIPK4
UniProt Protein Name
Homeodomain-interacting protein kinase 4
UniProt Gene Name
HIPK4
NCBI Protein Information
homeodomain-interacting protein kinase 4

NCBI Summary for HIPK4

This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016]
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UniProt Comments for HIPK4

Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (). May act as a corepressor of transcription factors (Potential).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HIPK4 recombinant protein

 Reference Product  PubMed Publications
 BIRC5 recombinant protein  >1 publications with HIPK4 and BIRC5

Diseases associated with HIPK4 recombinant protein

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1 publications with HIPK4 and Fibrosis

Organs/Tissues associated with HIPK4 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with HIPK4 and Lung
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